Delavirdine
- BP-S-6-Medicinal Chemistry III
- Mar 31
- 1 min read
Chemical Structure / Formula of Delavirdine
Formula: C22H28N6O3
Structure: An NNRTI with a pyridine core.
Mechanism of Action
Binds directly to HIV-1 reverse transcriptase, preventing DNA synthesis.
Uses
HIV/AIDS therapy (HAART regimen, rarely used today).
Side Effects
Rash, hepatotoxicity.
GI upset, headache.
Inhibits CYP3A4 (drug interactions).
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