Etidocaine

Etidocaine is a long-acting amide local anesthetic used for surgical anesthesia and nerve blocks.

Structure of Etidocaine

• It is an amide-type local anesthetic with an extended diethylaminoethyl side chain, providing prolonged anesthetic effects.
• Chemical Formula: C₁₅H₂₈N₂O

Mode of Action

• Sodium Channel Inhibition: Blocks voltage-gated sodium channels, preventing nerve impulse propagation.
• Membrane Stabilization: Reduces nerve excitability by enhancing membrane stability.

Uses

• Local Anesthesia: Used in dental procedures, minor surgeries, and obstetric anesthesia for prolonged numbness.
• Topical Preparations: Applied to skin and mucous membranes for extended local pain relief.
• Infiltration Anesthesia: Injected to provide sustained localized anesthesia during medical procedures.

Side Effects of Etidocaine

• Local Reactions: Redness, swelling, or irritation at the injection site.
• Systemic Toxicity: Potential CNS excitation (e.g., seizures) and cardiovascular effects (e.g., arrhythmias) with excessive doses.

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