Meprylcaine

Meprylcaine is an ester-type local anesthetic that provides surface and infiltration anesthesia by blocking nerve impulse conduction.

Structure of Meprylcaine

• It is a synthetic local anesthetic with a diethylaminoethyl substituent attached to a benzamide core.
• Chemical Formula: C₁₁H₂₂N₂O

Mode of Action

• Sodium Channel Blockade: Inhibits nerve impulse transmission by blocking voltage-gated sodium channels.
• Extended Duration: Provides longer-lasting anesthesia compared to simpler Local Anesthetics.

Uses

• Local Anesthesia: Used in minor surgical procedures and dental applications.
• Topical Preparations: Applied to mucous membranes for numbing before procedures.

Side Effects of Meprylcaine

• Central Nervous System Effects: Dizziness, tremors, and seizures with excessive use.
• Cardiovascular Toxicity: Hypotension and arrhythmias in high doses.

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