Piperocaine

Piperocaine is an ester-type local anesthetic used for infiltration and surface anesthesia by blocking nerve conduction.

Structure of Piperocaine

• It is a synthetic local anesthetic with a piperidine ring attached to a benzamide core, enhancing its anesthetic potency and duration.
• Chemical Formula: C₁₀H₂₁N₃O

Mode of Action

• Sodium Channel Inhibition: Blocks voltage-gated sodium channels, preventing nerve impulse propagation.
• Enhanced Potency: More potent than benzocaine due to structural modifications.

Uses

• Dental Anesthesia: Employed in dental procedures for effective local numbing.
• Ophthalmic Procedures: Used in eye surgeries for corneal anesthesia.
• Minor Surgical Procedures: Applied in small-scale surgical interventions requiring local anesthesia.

Side Effects of Piperocaine

• Central Nervous System Effects: Dizziness, tremors, and in severe cases, seizures.
• Cardiovascular Toxicity: Hypotension and arrhythmias with high doses.

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