Preparation of Ointments
- S-1-Pharmaceutics I
- Feb 27
- 1 min read
Updated: Apr 9
Ointments are semi-solid preparations used topically on the skin or mucous membranes to provide a protective, soothing, or therapeutic effect.
They are typically composed of an oily or greasy base, which helps to retain moisture, and may contain active ingredients to treat various conditions or ailments.
Ointments are widely used in dermatology, wound care, and other medical applications.
Preparation
Ointments can be prepared using various methods, with the most common being fusion, levigation, and incorporation.
1) Fusion
This involves melting the ingredients together, with the base being heated first, followed by the addition of other ingredients.
Once the mixture is homogeneous, it is allowed to cool and solidify.
This method is used for preparing ointments with components that need to be melted together.
2) Levigation
This involves triturating (grinding) a solid ingredient into a fine powder and then mixing it with the ointment base.
The fine powder ensures that the active ingredient is evenly distributed throughout the ointment.
Types
Ointments can be broadly classified into four main types, based on their base composition:
Oleaginous (oil-based) ointments
Absorption ointments
Water-removable (water-washable) ointments
Water-soluble ointments
Uses
Ointments have a wide range of uses, including:
Protection
Moisturization
Wound care
Pain relief
Antifungal and antiviral treatments
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