Industrial Pharmacy I

Quality Control Tests for Packaging Materials

  • Quality Control Tests for Packaging Materials ensure strength, integrity, and compatibility by assessing parameters like tensile strength, thickness, and permeability.
  • Quality Control Tests for Packaging Materials also check microbial contamination, chemical reactivity, and environmental stability to maintain product safety and compliance.
  • Robust quality control (QC) testing is essential to ensure that packaging components meet the stringent requirements for pharmaceutical applications:
  • To ensure safety and suitability, the following tests are conducted:
  1. Glass

    • Chemical Resistance Test: Measures resistance to alkali leaching.
    • Thermal Shock Test: Assesses durability against sudden temperature changes.
  2. Plastics

    • Tensile Strength Test: Evaluates strength and flexibility.
    • Permeability Test: Measures moisture and gas transmission rates.
    • Extractables and Leachables Test: Identifies substances that may migrate into the drug.
  3. Rubber

    • Penetration Test: Assesses resealing ability after needle puncture.
    • Compression Set Test: Evaluates elasticity after prolonged compression.
  4. Aluminum Foil

    • Pin Hole Test: Detects imperfections in the foil.
    • Bursting Strength Test: Measures resistance to applied pressure.
  5. Paper and Board

    • Moisture Content Test: Determines resistance to environmental humidity.
    • Tear Resistance Test: Evaluates durability under stress.

 

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