Voglibose

Voglibose is an alpha-glucosidase inhibitor antidiabetic drug that helps control post-meal blood sugar by delaying carbohydrate absorption.

Structure of Voglibose

• It is an iminosugar derivative with a cyclitol backbone, structurally modified to enhance specificity for intestinal alpha-glucosidases.
• Chemical Formula: C₁₂H₂₀N₂O₈

Mode of Action

• Alpha-Glucosidase Inhibition: Specifically inhibits intestinal enzymes, delaying carbohydrate digestion.
• Postprandial Glycemic Control: Prevents rapid spikes in blood glucose after meals.

Uses

• Type 2 Diabetes Mellitus: Effective in managing postprandial hyperglycemia.
• Combination Therapy: Often combined with other antidiabetic agents for comprehensive glycemic management.

Side Effects of Voglibose

• Gastrointestinal Issues: Bloating, diarrhea, and flatulence due to fermentation of undigested carbohydrates.

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