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Recently Uploaded Topics
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Absorption of Drugs
Absorption of Drugs refers to the process by which a drug enters the bloodstream from its site of administration. Factors Affecting Absorption: Route of Administration: Oral, IV, IM, subcutaneous, transdermal, inhalational, etc. IV route bypasses absorption as the drug is delivered directly into the bloodstream. Physicochemical Properties of the Drug: Solubility (lipid vs. water solubility)…
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Allergy (Drug Hypersensitivity)
Allergy (Drug Hypersensitivity) is an abnormal immune reaction to a drug, causing effects like rash, swelling, or anaphylaxis. Definition of Drug Hypersensitivity: A drug allergy is an immune system-mediated adverse drug reaction. It can occur at low doses, is unpredictable, and is not related to the pharmacologic action of the drug. Types of Hypersensitivity Reactions…
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Distribution of Drugs
Distribution is the reversible transfer of a drug from the bloodstream to various tissues and organs. Once absorbed, drugs distribute throughout the body, moving into different tissues and fluids. Distribution depends on: Blood Flow (Perfusion Rate) Organs with higher blood flow (brain, liver, kidneys) get drug supply more rapidly. Skeletal muscle, adipose tissue, and skin…
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