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Recently Uploaded Topics
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Hyperuricemia
Hyperuricemia is a condition of elevated uric acid levels in the blood, caused by excess production or reduced excretion. Uric acid, the end product of purine metabolism, is primarily excreted by the kidneys, and its buildup can lead to gout and kidney stones. Causes of Hyperuricemia Increased Uric Acid Production: High purine diet (red meat,…
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Catabolism of Purine Nucleotides
Catabolism of Purine Nucleotides involves the breakdown of nucleotides into their constituent components, ultimately leading to the formation of uric acid. Catabolism of Purine Nucleotides process occurs mainly in the liver and involves several key enzymes. Steps in Purine Catabolism Degradation of AMP and GMP: AMP Catabolism: AMP is deaminated to inosine monophosphate (IMP) by…
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Biosynthesis of Pyrimidine Nucleotide
Biosynthesis of Pyrimidine Nucleotide is the biochemical process through which cells produce pyrimidine bases cytosine, thymine, and uracil used to form nucleotides such as UMP (uridine monophosphate), CMP (cytidine monophosphate), and TMP (thymidine monophosphate). Biosynthesis of Pyrimidine Nucleotide is synthesized first and then attached to a ribose-phosphate backbone. De Novo Pathway The de novo synthesis of pyrimidines…
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