Pharmaceutical Biotechnology Notes (S-6)
Pharmaceutical Biotechnology Notes
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Unit 1
Introduction to Pharmaceutical Biotechnology
Overview of biotech in pharma, enzyme immobilization methods & uses, biosensor functions & applications, intro to protein engineering, industrial use of microbes, enzyme production (e.g., amylase, lipase), and basics of genetic engineering.

Unit 2
Genetic Engineering & rDNA Technology
Covers cloning vectors, restriction enzymes, DNA ligase, recombinant DNA tech, medical applications, genetic engineering for interferon, hepatitis-B vaccine, insulin production, and an intro to PCR.

Unit 3
Immunology and Vaccine Technology
This unit Covers humoral & cellular immunity, immunoglobulin & MHC structure, hypersensitivity, immune modulation, vaccine/toxoid prep, storage/stability of vaccines, hybridoma tech, and blood products/plasma substitutes.

Unit 4
Microbial Genetics & Biotransformation
This unit Covers immunoblotting (ELISA, Western, Southern), genetic setup of prokaryotes & eukaryotes, microbial genetics (transformation, transduction, conjugation, plasmids, transposons), microbial biotransformation, and mutation types

Unit 5
Fermentation & Bioproduct Production
Unit 5 Covers fermentation methods, media, equipment, sterilization, aeration, stirring, large-scale fermenter design, production of penicillin, citric acid, Vitamin B12, glutamic acid, griseofulvin, and handling of blood products and plasma substitutes
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