Precipitation Titrations, Gravimetry Analysis U-3

Precipitation titrations

• Introduction
• Mohr’s method
• Volhard’s method
• Modified Volhard’s Method (Direct Volhard’s Method)
• Fajans Method (Adsorption Indicator Method)
• Estimation of sodium chloride

Complexometric titration

• Introduction: Complexometric Titration
• Classification of Complexometric Titrations
• Metal ion indicators
• Masking and demasking reagents
• Estimation of Magnesium Sulfate by Complexometric Titration
• Estimation of Calcium Gluconate by Complexometric Titration

Gravimetry

• Gravimetric Analysis: Principle and Steps
• Purity of the precipitate: co-precipitation and post precipitation
• Estimation of Barium Sulphate (BaSO₄)
• Diazotization titration

Other Units of Pharmaceutical analysis I

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Other Subjects of B Pharmcy Semester 1

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Unit I – Complexometric Titrations, Gravimetry Analysis Details

Pharmaceutical Analysis I – BPharma 1st Semester (AKTU & PCI Syllabus)

At FirstHope, we offer precise, exam-oriented notes aligned with the PCI-approved B Pharma syllabus. Unit I of Pharmaceutical Analysis introduces key concepts like concentration methods, standard solutions, and analytical errors. Therefore, a strong grasp of this unit is vital for semester success and exams like GPAT and NIPER.

1. Precipitation Titrations

This section explains titrations based on the formation of a precipitate. It includes Mohr’s method, Volhard’s method, Modified Volhard’s, and Fajans method. These are mainly used for the estimation of sodium chloride (NaCl) by forming a silver chloride precipitate.

2. Complexometric Titrations

Here, titrations involve complex formation between metal ions and chelating agents like EDTA. The section covers classification, use of metal ion indicators, and masking/demasking reagents. It also explains the estimation of magnesium sulphate and calcium gluconate in pharmaceutical analysis.

3. Gravimetry and Diazotisation Titrations

Gravimetric analysis is based on weighing a precipitate to determine the amount of analyte. It includes steps involved, co-precipitation, and post-precipitation, with barium sulphate estimation as an example. The unit also introduces diazotisation titration, its principles, methods, and pharmaceutical applications.

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