Autocoids and Related Drugs U-3 Notes

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Autacoids and related drugs

  • Introduction to Autacoids
  • Classification of Histamine
  • 5-HT (5-Hydroxytryptamine) (Serotonin)

Prostaglandins, Thromboxanes, and Leukotrienes

  • Prostaglandins
  • Thromboxanes
  • Leukotrienes

Angiotensin, Bradykinin, and Substance P

  • Angiotensin
  • Bradykinin
  • Substance P
  • Non-Steroidal Anti-Inflammatory Agents (NSAIDs)
  • Aspirin

Antigout Drugs and Anti-Rheumatic Drugs

  • Antigout Drugs
  • Anti-Rheumatic Drugs

Other Units of Pharmacology II

Unit 1
Unit 2
Unit 4
Unit 5
Pharmacology II

Other Subjects of B Pharmacy 5th Semester

Topic wise notes of:

Medicinal Chemistry II

  • Anti-Histaminic & Anti-Neoplastic Agents
  • Anti-Anginal & Diuretics
  • Anti-Arrhythmic & Anti-Hyperlipidemic Agents
  • Drugs on Endocrine System, Sexual Health, Corticosteroids
  • Anti-Diabetic & Local Anaesthetic Agents
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Pharmaceutical Jurisprudence

Topic wise notes of:

Pharmaceutical Jurisprudence

  • Drugs and Cosmetics Act, 1940 and its rules 1945
  • Schedules under the Drugs and Cosmetics Act
  • Medicinal Preparations, and Narcotic Regulations in India
  • Drugs and Magic Remedies, Animal Ethics, Price Regulation
  • Pharmaceutical Legislation, Ethics, and Legal Rights
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Secondary Metabolites in pharmacognosy & phytochemistry II

Topic wise notes of:

Pharmacognosy & Phytochemistry II

  • Metabolic Pathways and Biogenesis of Secondary Metabolites
  • Secondary Metabolites: Classification, Sources and Applications
  • Isolation, Identification of Key Phytoconstituents
  • Industrial Production of Essential Phytoconstituents
  • Modern Extraction Techniques
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Topic wise notes of:

Industrial Pharmacy I

  • Pre-Formulation Studies
  • Tablets & Liquid Orals
  • Hard & Soft Gelatin Capsules, Pellets
  • Parenteral Products & Ophthalmic preparations
  • Cosmetic, Pharmaceutical Aerosols & Packaging Materials
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Unit III: Autocoids and Related Drugs – Summary

This unit focuses on autocoids, a diverse group of biologically active substances involved in inflammation, allergy, and pain mechanisms. It’s a key topic for students preparing BPharma 5th semester exams and GPAT.

Key Concepts Covered:

  • Introduction & Classification of Autocoids: Autocoids are locally acting hormones like histamine, serotonin, prostaglandins, and kinins, playing roles in physiological and pathological processes.
  • Histamine and 5-HT (Serotonin): Their functions and antagonists such as antihistamines (H1 and H2 blockers) and serotonin receptor blockers are discussed.
  • Prostaglandins, Thromboxanes & Leukotrienes: Learn about their roles in inflammation, fever, and pain, along with drugs that inhibit their synthesis.
  • Angiotensin, Bradykinin, Substance P: Explore peptides that influence blood pressure and inflammation.
  • NSAIDs (Non-Steroidal Anti-Inflammatory Drugs): Includes aspirin, ibuprofen, and COX-2 inhibitors used to treat inflammation and pain.
  • Anti-gout and Antirheumatic Drugs: Covers colchicine, allopurinol, and DMARDs used in treating chronic inflammatory conditions.

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