Surface, Interfacial Phenomenon U-3 Notes
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Surface and Interfacial Phenomenon
- Surface and Interfacial Phenomena in Pharmaceutical Sciences
- Liquid Interface
- Surface and Interfacial Tensions
- Surface Free Energy
- Measurement of Surface and Interfacial Tensions
- Spreading Coefficient
- Adsorption at Liquid Interfaces
- Surface-Active Agents (Surfactants)
- Hydrophile-Lipophile Balance (HLB) Scale
- Solubilization
- Detergency
- Adsorption at Solid Interfaces
Other Units of Physical Pharmaceutics I
Physical Pharmaceutics I
Other Subjects of B Pharmacy 3rd Semester
Topic wise notes of:
Pharmaceutical Organic Chemistry II
- Benzene & It’s Derivative
- Phenols, Aromatic Amines & Acids
- Fats & Oils
- Polynuclear Hydrocarbons
- Cycloalkanes
Topic wise notes of:
Pharmaceutical Engineering
Topic wise notes of:
Pharmaceutical Microbiology
- Microbiology and Bacterial Cultivation Techniques
- Sterilization Techniques and Staining Methods
- Fungi, Viruses, and Sterility
- Aseptic Area and Assay Methods
- Microbial Spoilage & Cell Culture
Unit III Summary: Surface and Interfacial Phenomena
Unit III focuses on the principles of surface and interfacial phenomena, which are critical in pharmaceutical formulation and product stability. It begins with the study of liquid interfaces, explaining the concepts of surface tension and interfacial tension, which arise due to the imbalance of molecular forces at the surface or boundary between two phases.
The unit explores surface free energy and its role in determining the stability and behavior of interfaces. It includes methods for measuring surface and interfacial tension, which are essential for characterizing liquids and formulations. The concept of spreading coefficient is introduced to evaluate how one liquid spreads over another.
A significant portion of the unit covers adsorption at liquid interfaces, particularly the role of surface-active agents (surfactants), which reduce surface tension and enhance solubility. The Hydrophilic-Lipophilic Balance (HLB) scale is discussed as a tool for selecting appropriate surfactants. Additional topics include solubilization, detergency, and adsorption at solid interfaces, which are crucial in drug delivery, emulsions, and cleansing formulations.
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