Buy Premium

Get The High-Quality Pdf Notes on App


Physical Pharmaceutics I

Other Subjects of B Pharmacy 3rd Semester

Topic wise notes of:

Pharmaceutical Organic Chemistry II


Topic wise notes of:

Pharmaceutical Microbiology

Unit III Summary: Surface and Interfacial Phenomena

Unit III focuses on the principles of surface and interfacial phenomena, which are critical in pharmaceutical formulation and product stability. It begins with the study of liquid interfaces, explaining the concepts of surface tension and interfacial tension, which arise due to the imbalance of molecular forces at the surface or boundary between two phases.

The unit explores surface free energy and its role in determining the stability and behavior of interfaces. It includes methods for measuring surface and interfacial tension, which are essential for characterizing liquids and formulations. The concept of spreading coefficient is introduced to evaluate how one liquid spreads over another.

A significant portion of the unit covers adsorption at liquid interfaces, particularly the role of surface-active agents (surfactants), which reduce surface tension and enhance solubility. The Hydrophilic-Lipophilic Balance (HLB) scale is discussed as a tool for selecting appropriate surfactants. Additional topics include solubilization, detergency, and adsorption at solid interfaces, which are crucial in drug delivery, emulsions, and cleansing formulations.

At FirstHope, we provide BPharm notes that are topic-wise, easy to understand, and designed strictly as per the AKTU and Other Universities, hence designed according to PCI syllabus.

Thank you for reading from Firsthope's notes, don't forget to check YouTube videos!