CNS Drugs: Anesthetics, Analgesics and Anti-Inflammatories U-5 Notes
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General Anesthetics
Various Inhalation Anesthetics
Various Ultra-Short Acting Barbiturates
Various Dissociative Anesthetic
Narcotic and non-narcotic analgesics
Various Morphine and Related Drugs
- Morphine Sulphate
- Codeine
- Meperidine Hydrochloride (Pethidine)
- Anileridine Hydrochloride
- Diphenoxylate Hydrochloride
- Loperamide Hydrochloride
- Fentanyl Citrate
- Methadone Hydrochloride
- Propoxyphene Hydrochloride
- Pentazocine
- Levorphanol Tartrate
Various Narcotic (Opioid) Antagonists
Various Anti-Inflammatory Agents (NSAIDs)
- Sodium Salicylate
- Aspirin (Acetylsalicylic acid)
- Mefenamic Acid*
- Meclofenamate (Meclofenamic acid)
- Indomethacin
- Sulindac
- Tolmetin
- Zomepirac (Withdrawn)
- Diclofenac
- Ketorolac
- Ibuprofen
- Naproxen
- Piroxicam
- Phenacetin (Withdrawn)
- Acetaminophen (Paracetamol)
- Antipyrine
- Phenylbutazone
Other Units of Medicinal Chemistry I
Medicinal Chemistry I
Other Subjects of B Pharmacy 4th Semester
Topic wise notes of:
Pharmacology I
- Introduction to Pharmacology & Pharmacokinetics
- Pharmacodynamics & Drug Interaction
- Pharmacology of drugs acting on peripheral nervous system
- Pharmacology of drugs acting on central nervous system-1
- Psychotropic Drugs
Topic wise notes of:
Physical Pharmaceutics II
- Colloidal dispersions
- Rheology & Deformation of solids
- Coarse dispersion
- Micromeretics
- Drug stability
Topic wise notes of:
Pharmacognosy & Phytochemistry I
- Pharmacognosy: Sources, Classification, and Quality Control
- Conservation and Cultivation of Medicinal Plants
- Plant tissue culture
- Role of Pharmacognosy and Secondary Metabolites
- Drugs of Natural Origin: Plant, Marine, and Primary Metabolites
Topic wise notes of:
Pharmaceutical Organic Chemistry III
- Stereo isomerism
- Geometrical isomerism
- Heterocyclic compounds
- Heterocycles: Synthesis, Reactions & Uses
- Reactions of synthetic importance
CNS-Acting Drugs: Anesthetics, Analgesics, and Anti-Inflammatories – Summary
Unit V provides a comprehensive overview of CNS-acting drugs, with a focus on general anesthetics, analgesics, and anti-inflammatory agents. It begins with inhalation anesthetics such as halothane, enflurane, sevoflurane, isoflurane, and desflurane, explaining their roles in inducing and maintaining anesthesia during surgeries.
The unit also covers ultra-short acting barbiturates like methohexital, thiamylal, and thiopental sodium, which are used for induction of anesthesia. Additionally, it introduces dissociative anesthetics such as ketamine, known for its unique anesthetic and analgesic properties.
Next, the unit shifts to narcotic and non-narcotic analgesics, emphasizing the Structure-Activity Relationship (SAR) of morphine and its analogues. Drugs like codeine, fentanyl, methadone, loperamide, and meperidine are discussed for their pain-relieving properties. It also includes narcotic antagonists like naloxone, used to reverse opioid overdose.
Lastly, the unit details various anti-inflammatory agents, including aspirin, ibuprofen, diclofenac, naproxen, piroxicam, and acetaminophen. These drugs are key in managing pain, inflammation, and fever. This unit equips students with essential knowledge about the chemical and pharmacological aspects of CNS-active anesthetics and analgesics.
Overall, this unit gives a thorough understanding of cholinergic pharmacology and its clinical applications.
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