Reactions of synthetic importance U-5 Notes
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Reactions of synthetic importance
- Metal Hydride Reduction (NaBH₄ and LiAlH₄)
- Clemmensen Reduction
- Birch Reduction
- Wolff–Kishner Reduction
- Oppenauer Oxidation
- Dakin Reaction
- Beckmann Rearrangement
- Schmidt Rearrangement
- Claisen–Schmidt Condensation
Other Units of Pharmaceutical Organic Chemistry III
Pharmaceutical Organic Chemistry III
Other Subjects of B Pharmacy 4th Semester
Topic wise notes of:
Medicinal Chemistry I
- Fundamentals of Medicinal Chemistry
- Drugs Acting on the Adrenergic Nervous System
- Cholinergic neurotransmitters
- Drugs acting on Central Nervous System
- CNS Drugs: Anesthetics, Analgesics and Anti-Inflammatories
Topic wise notes of:
Physical Pharmaceutics II
- Colloidal dispersions
- Rheology & Deformation of solids
- Coarse dispersion
- Micromeretics
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Topic wise notes of:
Pharmacology I
- Introduction to Pharmacology & Pharmacokinetics
- Pharmacodynamics & Drug Interaction
- Pharmacology of drugs acting on peripheral nervous system
- Pharmacology of drugs acting on central nervous system-1
- Pharmacology of drugs acting on central nervous system-2
Topic wise notes of:
Pharmacognosy & Phytochemistry I
- Pharmacognosy: Sources, Classification, and Quality Control
- Cultivation and Conservation of Medicinal Plants
- Plant tissue culture
- Role of Pharmacognosy and Secondary Metabolites
- Drugs of Natural Origin: Plant, Marine, and Primary Metabolites
Unit V: Reactions of synthetic importance – Easy Summary
Unit V talks about some important chemical reactions used to make medicines and other useful compounds. These reactions help change one chemical into another, which is very useful in drug design and preparation.
The unit starts with metal hydride reduction, which is a method to turn certain groups in a molecule into alcohols. A common chemical used in this is sodium borohydride (NaBH₄). This reaction is mild and works well in many cases.
Next is the Wolff-Kishner reduction, which removes a group called a carbonyl from a molecule. This reaction uses strong base and heat to make big changes in the structure.
The Oppenauer oxidation is the opposite of reduction. It changes alcohols into ketones or aldehydes. This is helpful when preparing a molecule for further reactions.
The Dakin reaction is used to make phenols from aldehydes, especially when a hydroxyl group is close by.
Then, the unit explains Beckmann and Schmidt rearrangements. These reactions move atoms around inside a molecule to create new, useful structures like amides and lactams.
Finally, the Claisen-Schmidt condensation joins two molecules together to form larger, more complex ones. This is important for making things like fragrances, dyes, and some drugs.
These reactions are simple tools that help chemists build useful compounds step by step.
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