Drugs acting on peripheral nervous system U-3 Notes

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Drugs Acting on the Peripheral Nervous
System (PNS)

  • What is the Peripheral Nervous System?
  • Organization of the ANS
  • Function of ANS (Autonomic Nervous System)
  • Neurohumoral Transmission
  • Co-transmission
  • Classification of Neurotransmitters
  • Parasympathomimetic Drugs (Cholinergic Agonists)
  • Parasympatholytic Drugs
  • Sympathomimetic Drugs
  • Sympatholytic Drugs
  • Neuromuscular Blocking Agents (NMBAs)
  • Skeletal Muscle Relaxants (Peripheral)
  • Local Anesthetic Agents
  • Myasthenia Gravis (MG)
  • Glaucoma
  • Drugs Used in Glaucoma

Other Units of Pharmacology I

Unit 1
Unit 2
Unit 4
Unit 5
Pharmacology I

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Pharmacognosy & Phytochemistry I

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Pharmaceutical Organic Chemistry III

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Pharmacology of Drugs Acting on the Peripheral Nervous System – Summary

Unit III focuses on the pharmacology of drugs acting on the peripheral nervous system (PNS), emphasizing the autonomic nervous system (ANS) and its regulation of vital functions. It begins with an overview of the organization and functions of the ANS, which includes the sympathetic and parasympathetic divisions responsible for involuntary physiological responses.

The unit explains neurohumoral transmission, detailing how nerve impulses are transmitted via neurotransmitters. It also introduces the concept of co-transmission, where multiple neurotransmitters are released simultaneously, and provides a classification of neurotransmitters based on their structure and function.

Further, the unit explores four major classes of autonomic drugs: parasympathomimetics and parasympatholytics, which stimulate or block parasympathetic activity, and sympathomimetics and sympatholytics, which enhance or inhibit sympathetic activity. These drugs are essential in treating conditions such as asthma, hypertension, and bradycardia.

Moreover, the pharmacology of neuromuscular blocking agents and skeletal muscle relaxants is discussed, focusing on drugs that affect voluntary muscle control. The unit also covers local anesthetics, which block nerve conduction, and their use in surgical and dental procedures.

Finally, drugs used in specific neuromuscular disorders like myasthenia gravis and glaucoma are included, emphasizing their therapeutic mechanisms and clinical importance in managing these conditions.

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