Autocoids and Related Drugs Notes [U-3]
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Autacoids and related drugs
Prostaglandins, Thromboxanes, and Leukotrienes
Angiotensin, Bradykinin, and Substance P
Antigout Drugs and Anti-Rheumatic Drugs
Other Units of Pharmacology II
Pharmacology II
Other Subjects of B Pharmacy 5th Semester
Topic wise notes of:
Medicinal Chemistry II
- Anti-Histaminic & Anti-Neoplastic Agents
- Anti-Anginal & Diuretics
- Anti-Arrhythmic & Anti-Hyperlipidemic Agents
- Drugs on Endocrine System, Sexual Health, Corticosteroids
- Anti-Diabetic & Local Anaesthetic Agents
Topic wise notes of:
Pharmaceutical Jurisprudence
- Drugs and Cosmetics Act, 1940 and its rules 1945
- Schedules under the Drugs and Cosmetics Act
- Medicinal Preparations, and Narcotic Regulations in India
- Drugs and Magic Remedies, Animal Ethics, Price Regulation
- Pharmaceutical Legislation, Ethics, and Legal Rights
Topic wise notes of:
Pharmacognosy & Phytochemistry II
- Metabolic Pathways and Biogenesis of Secondary Metabolites
- Secondary Metabolites: Classification, Sources and Applications
- Isolation, Identification of Key Phytoconstituents
- Industrial Production of Essential Phytoconstituents
- Modern Extraction Techniques
Topic wise notes of:
Industrial Pharmacy I
- Pre-Formulation Studies
- Tablets & Liquid Orals
- Hard & Soft Gelatin Capsules, Pellets
- Parenteral Products & Ophthalmic preparations
- Cosmetic, Pharmaceutical Aerosols & Packaging Materials
Unit III: Autocoids and Related Drugs – Summary
This unit focuses on autocoids, a diverse group of biologically active substances involved in inflammation, allergy, and pain mechanisms. It’s a key topic for students preparing BPharma 5th semester exams and GPAT.
Key Concepts Covered:
- Introduction & Classification of Autocoids: Autocoids are locally acting hormones like histamine, serotonin, prostaglandins, and kinins, playing roles in physiological and pathological processes.
- Histamine and 5-HT (Serotonin): Their functions and antagonists such as antihistamines (H1 and H2 blockers) and serotonin receptor blockers are discussed.
- Prostaglandins, Thromboxanes & Leukotrienes: Learn about their roles in inflammation, fever, and pain, along with drugs that inhibit their synthesis.
- Angiotensin, Bradykinin, Substance P: Explore peptides that influence blood pressure and inflammation.
- NSAIDs (Non-Steroidal Anti-Inflammatory Drugs): Includes aspirin, ibuprofen, and COX-2 inhibitors used to treat inflammation and pain.
- Anti-gout and Antirheumatic Drugs: Covers colchicine, allopurinol, and DMARDs used in treating chronic inflammatory conditions.
At FirstHope, we provide BPharm notes that are topic-wise, easy to understand, and designed strictly as per the AKTU and Other Universities, hence designed according to PCI syllabus.



