Immunology and Vaccine Technology Notes [U-3]

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Immunity

  • Immunity
  • Humoral Immunity
  • Cellular Immunity (Cell-Mediated Immunity)
  • Structure of Immunoglobulins (Antibodies)
  • Structure and Function of MHC (Major Histocompatibility Complex)
  • Hypersensitivity reaction
  • Immune stimulation
  • Immune suppressions

General Methods of Preparation of Immunological Products

  • Preparation of Bacterial Vaccines
  • Toxoids (Detoxified Bacterial Toxins for Vaccination)
  • Preparation of Viral Vaccines
  • Antitoxins (Passive Immunity Against Toxins)
  • Serum-Immune Blood Derivatives (Passive Immunization)
  • Storage Conditions and Stability of Official Vaccines
  • Hybridoma Technology: Production, Purification, and Applications
  • Blood Products
  • Plasma Substitutes
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Other Units of Pharmaceutical Biotechnology

Unit 1
Unit 2
Unit 4
Unit 5
Pharmaceutical Biotechnology
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Other Subjects of B Pharmacy 6th Semester

Herbal Drug Technology

Topic wise notes of:

Herbal Drug Technology

  • Herbal Raw Materials & Indian Medicine Systems
  • Nutraceuticals: Uses, Herbs & Interactions
  • Herbal Cosmetics, Excipients & Formulations
  • Herbal Drug Evaluation, Patents & Regulations
  • Herbal Industry: Scope, GMP & Infrastructure
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Absorption & Distribution

Topic wise notes of:

Biopharmaceutics and Pharmacokinetics

  • Biopharmaceutics: Absorption & Distribution
  • Drug Elimination, Bioavailability & Bioequivalence
  • Pharmacokinetics Models, Dosing & Parameters
  • Multicompartment models
  • Nonlinear Pharmacokinetics
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Pharmacology III Respiratory and GI Tract

Topic wise notes of:

Pharmacology III

  • Respiratory & GI Tract Drug Pharmacology
  • Chemotherapy: Principles & Key Antibiotics
  • Chemotherapy: TB, Fungal & Parasitic Drugs
  • UTIs, Cancer Chemo & Immunopharmacology
  • Toxicology Basics & Chrono pharmacology
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Antibiotics & Aminoglycosides in Medicinal Chemistry III

Topic wise notes of:

Medicinal Chemistry III

  • Antibiotics & Aminoglycosides
  • Antibiotics & Antimalarials: Structures & SAR
  • Anti-TB, UTI & Antiviral Agents
  • Antifungals, Antiprotozoals & Sulfonamides
  • Intro to Drug Design & QSAR Approaches
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Pharmaceutical Quality Assurance

Topic wise notes of:

Pharmaceutical Quality Assurance

  • Quality Assurance, GMP, ICH, QbD & Quality System
  • GMP: Personnel, Premises & Equipment Control
  • Quality Control and Good Laboratory Practice
  • Complaints & Document Management
  • Calibration and Warehousing
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Types of Immunity and Immunological Applications – Notes

  1. Types of Immunity:
    • Humoral Immunity: Mediated by antibodies produced by B cells.
    • Cellular Immunity: Involves T cells that attack infected or abnormal cells.
  2. Immunoglobulin Structure:
    • Composed of two heavy and two light chains.
    • Contains variable (antigen-binding) and constant regions.
  3. MHC Structure & Function:
    • MHC I: Found on all nucleated cells; presents antigens to CD8+ T cells.
    • MHC II: Found on antigen-presenting cells; presents to CD4+ T cells.
  4. Immune Responses:
    • Hypersensitivity: Exaggerated immune reactions (Types I–IV).
    • Stimulation: Enhances immune defense.
    • Suppression: Reduces unwanted immune activity (e.g., autoimmune diseases).
  5. Vaccine & Serum Preparation:
    • Methods vary for bacterial/viral vaccines, toxoids, antitoxins, and immune sera.
  6. Vaccine Storage:
    • Requires controlled temperatures to maintain potency and stability.
  7. Hybridoma Technology:
    • Produces monoclonal antibodies for diagnostics and therapy.
  8. Blood Products & Plasma Substitutes:
    • Used in transfusions and for volume replacement in clinical settings

At FirstHope, we provide BPharm notes that are topic-wise, easy to understand, and designed strictly as per the AKTU and Other Universities, hence designed according to PCI syllabus.

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