Immunology and Vaccine Technology Notes [U-3]
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Immunity
- Immunity
- Humoral Immunity
- Cellular Immunity (Cell-Mediated Immunity)
- Structure of Immunoglobulins (Antibodies)
- Structure and Function of MHC (Major Histocompatibility Complex)
- Hypersensitivity reaction
- Immune stimulation
- Immune suppressions
General Methods of Preparation of Immunological Products
- Preparation of Bacterial Vaccines
- Toxoids (Detoxified Bacterial Toxins for Vaccination)
- Preparation of Viral Vaccines
- Antitoxins (Passive Immunity Against Toxins)
- Serum-Immune Blood Derivatives (Passive Immunization)
- Storage Conditions and Stability of Official Vaccines
- Hybridoma Technology: Production, Purification, and Applications
- Blood Products
- Plasma Substitutes
Other Units of Pharmaceutical Biotechnology
Pharmaceutical Biotechnology
Other Subjects of B Pharmacy 6th Semester
Topic wise notes of:
Biopharmaceutics and Pharmacokinetics
- Biopharmaceutics: Absorption & Distribution
- Drug Elimination, Bioavailability & Bioequivalence
- Pharmacokinetics Models, Dosing & Parameters
- Multicompartment models
- Nonlinear Pharmacokinetics
Topic wise notes of:
Medicinal Chemistry III
- Antibiotics & Aminoglycosides
- Antibiotics & Antimalarials: Structures & SAR
- Anti-TB, UTI & Antiviral Agents
- Antifungals, Antiprotozoals & Sulfonamides
- Intro to Drug Design & QSAR Approaches
Topic wise notes of:
Pharmaceutical Quality Assurance
- Quality Assurance, GMP, ICH, QbD & Quality System
- GMP: Personnel, Premises & Equipment Control
- Quality Control and Good Laboratory Practice
- Complaints & Document Management
- Calibration and Warehousing
Types of Immunity and Immunological Applications – Notes
- Types of Immunity:
- Humoral Immunity: Mediated by antibodies produced by B cells.
- Cellular Immunity: Involves T cells that attack infected or abnormal cells.
- Immunoglobulin Structure:
- Composed of two heavy and two light chains.
- Contains variable (antigen-binding) and constant regions.
- MHC Structure & Function:
- MHC I: Found on all nucleated cells; presents antigens to CD8+ T cells.
- MHC II: Found on antigen-presenting cells; presents to CD4+ T cells.
- Immune Responses:
- Hypersensitivity: Exaggerated immune reactions (Types I–IV).
- Stimulation: Enhances immune defense.
- Suppression: Reduces unwanted immune activity (e.g., autoimmune diseases).
- Vaccine & Serum Preparation:
- Methods vary for bacterial/viral vaccines, toxoids, antitoxins, and immune sera.
- Vaccine Storage:
- Requires controlled temperatures to maintain potency and stability.
- Hybridoma Technology:
- Produces monoclonal antibodies for diagnostics and therapy.
- Blood Products & Plasma Substitutes:
- Used in transfusions and for volume replacement in clinical settings
At FirstHope, we provide BPharm notes that are topic-wise, easy to understand, and designed strictly as per the AKTU and Other Universities, hence designed according to PCI syllabus.




