Introduction to Pharmaceutical Biotechnology Notes [U-1]

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Production of Specific Enzymes

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Pharmaceutical Biotechnology
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Other Subjects of B Pharmacy 6th Semester

Herbal Drug Technology

Topic wise notes of:

Herbal Drug Technology

  • Herbal Raw Materials & Indian Medicine Systems
  • Nutraceuticals: Uses, Herbs & Interactions
  • Herbal Cosmetics, Excipients & Formulations
  • Herbal Drug Evaluation, Patents & Regulations
  • Herbal Industry: Scope, GMP & Infrastructure

Absorption & Distribution

Topic wise notes of:

Biopharmaceutics and Pharmacokinetics

  • Biopharmaceutics: Absorption & Distribution
  • Drug Elimination, Bioavailability & Bioequivalence
  • Pharmacokinetics Models, Dosing & Parameters
  • Multicompartment models
  • Nonlinear Pharmacokinetics

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Pharmacology III Respiratory and GI Tract

Topic wise notes of:

Pharmacology III

  • Respiratory & GI Tract Drug Pharmacology
  • Chemotherapy: Principles & Key Antibiotics
  • Chemotherapy: TB, Fungal & Parasitic Drugs
  • UTIs, Cancer Chemo & Immunopharmacology
  • Toxicology Basics & Chrono pharmacology

Antibiotics & Aminoglycosides in Medicinal Chemistry III

Topic wise notes of:

Medicinal Chemistry III

  • Antibiotics & Aminoglycosides
  • Antibiotics & Antimalarials: Structures & SAR
  • Anti-TB, UTI & Antiviral Agents
  • Antifungals, Antiprotozoals & Sulfonamides
  • Intro to Drug Design & QSAR Approaches

Pharmaceutical Quality Assurance

Topic wise notes of:

Pharmaceutical Quality Assurance

  • Quality Assurance, GMP, ICH, QbD & Quality System
  • GMP: Personnel, Premises & Equipment Control
  • Quality Control and Good Laboratory Practice
  • Complaints & Document Management
  • Calibration and Warehousing

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Unit I: Introduction to Pharmaceutical Biotechnology Notes– Summary

Introduction to Biotechnology
Biotechnology uses living systems to create useful products. In pharmaceutical sciences, it helps make drugs, vaccines, and better treatments.

Enzyme Biotechnology
Enzymes speed up chemical reactions.

  • Immobilization Methods: Adsorption, covalent bonding, entrapment, encapsulation, and cross-linking help reuse enzymes and keep them stable.
  • Applications: Used in making antibiotics, vitamins, and other drugs.

Biosensors
Biosensors detect biological changes and convert them into signals.

  • How They Work: They combine a biological part (like an enzyme) with a detector.
  • Uses: Check glucose levels, monitor drug quality, and detect bacteria.

Microbes in Industry
Microbes help make many products.

  • Used For: Fermentation and enzyme production.
  • Examples of Enzymes:
    • Amylase: breaks down starch
    • Catalase and Peroxidase: break down harmful substances
    • Lipase: breaks down fats
    • Protease: breaks down proteins
    • Penicillinase: breaks penicillin

Genetic Engineering
Changes genes to make better products.

  • Tools: Vectors, restriction enzymes, and cloning.
  • Uses: Make insulin, vaccines, and gene therapies

At FirstHope, we provide BPharm notes that are topic-wise, easy to understand, and designed strictly as per the AKTU and Other Universities, hence designed according to PCI syllabus.

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