Introduction to Pharmaceutical Biotechnology Notes [U-1]

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Production of Specific Enzymes

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Pharmaceutical Biotechnology
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Other Subjects of B Pharmacy 6th Semester

Herbal Drug Technology

Topic wise notes of:

Herbal Drug Technology

  • Herbal Raw Materials & Indian Medicine Systems
  • Nutraceuticals: Uses, Herbs & Interactions
  • Herbal Cosmetics, Excipients & Formulations
  • Herbal Drug Evaluation, Patents & Regulations
  • Herbal Industry: Scope, GMP & Infrastructure

Absorption & Distribution

Topic wise notes of:

Biopharmaceutics and Pharmacokinetics

  • Biopharmaceutics: Absorption & Distribution
  • Drug Elimination, Bioavailability & Bioequivalence
  • Pharmacokinetics Models, Dosing & Parameters
  • Multicompartment models
  • Nonlinear Pharmacokinetics

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Pharmacology III Respiratory and GI Tract

Topic wise notes of:

Pharmacology III

  • Respiratory & GI Tract Drug Pharmacology
  • Chemotherapy: Principles & Key Antibiotics
  • Chemotherapy: TB, Fungal & Parasitic Drugs
  • UTIs, Cancer Chemo & Immunopharmacology
  • Toxicology Basics & Chrono pharmacology

Antibiotics & Aminoglycosides in Medicinal Chemistry III

Topic wise notes of:

Medicinal Chemistry III

  • Antibiotics & Aminoglycosides
  • Antibiotics & Antimalarials: Structures & SAR
  • Anti-TB, UTI & Antiviral Agents
  • Antifungals, Antiprotozoals & Sulfonamides
  • Intro to Drug Design & QSAR Approaches

Pharmaceutical Quality Assurance

Topic wise notes of:

Pharmaceutical Quality Assurance

  • Quality Assurance, GMP, ICH, QbD & Quality System
  • GMP: Personnel, Premises & Equipment Control
  • Quality Control and Good Laboratory Practice
  • Complaints & Document Management
  • Calibration and Warehousing

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Unit I: Introduction to Pharmaceutical Biotechnology Notesโ€“ Summary

Introduction to Biotechnology
Biotechnology uses living systems to create useful products. In pharmaceutical sciences, it helps make drugs, vaccines, and better treatments.

Enzyme Biotechnology
Enzymes speed up chemical reactions.

  • Immobilization Methods: Adsorption, covalent bonding, entrapment, encapsulation, and cross-linking help reuse enzymes and keep them stable.
  • Applications: Used in making antibiotics, vitamins, and other drugs.

Biosensors
Biosensors detect biological changes and convert them into signals.

  • How They Work: They combine a biological part (like an enzyme) with a detector.
  • Uses: Check glucose levels, monitor drug quality, and detect bacteria.

Microbes in Industry
Microbes help make many products.

  • Used For: Fermentation and enzyme production.
  • Examples of Enzymes:
    • Amylase: breaks down starch
    • Catalase and Peroxidase: break down harmful substances
    • Lipase: breaks down fats
    • Protease: breaks down proteins
    • Penicillinase: breaks penicillin

Genetic Engineering
Changes genes to make better products.

  • Tools: Vectors, restriction enzymes, and cloning.
  • Uses: Make insulin, vaccines, and gene therapies

At FirstHope, we provide BPharm notes that are topic-wise, easy to understand, and designed strictly as per the AKTU and Other Universities, hence designed according to PCI syllabus.

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