Respiratory & GI Tract Drug Pharmacology Notes [U-1]
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Pharmacology of drugs acting on Respiratory system
- Asthma
- Pharmacology of anti-asthmatic drugs
Drugs used in the management of COPD
- Total Quality Management (TQM)
- Philosophies of TQM
Expectorants and antitussives
- Cough
- Expectorants
- Antitussives
Nasal Decongestants
- Nasal Congestion
- Pharmacology of Nasal Decongestants
Respiratory Stimulants
- Respiratory Stimulants
- Classification of Respiratory Stimulants
Pharmacology of drugs acting on the Gastrointestinal Tract
- Ulcers
- Pharmacology of Antiulcer Agents
Drugs for constipation and diarrhoea
- Constipation
- Drugs for Constipation
- Diarrhoea
- Drugs for Diarrhoea
Appetite stimulants and suppressants
- Appetite
- Appetite Stimulants (Orexiants)
- Appetite Suppressants (Anorexiants)
Digestants and carminatives
- Digestants
- Carminatives
Emetics and Anti-Emetics
- Vomiting
- Emetics
- Antiemetics
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Other Units of Pharmaceutical Quality Assurance
Pharmacology III
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Other Subjects of B Pharmacy 6th Semester
Topic wise notes of:
Biopharmaceutics and Pharmacokinetics
- Biopharmaceutics: Absorption & Distribution
- Drug Elimination, Bioavailability & Bioequivalence
- Pharmacokinetics Models, Dosing & Parameters
- Multicompartment models
- Nonlinear Pharmacokinetics
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Topic wise notes of:
Pharmaceutical Quality Assurance
- Quality Assurance, GMP, ICH, QbD & Quality System
- GMP: Personnel, Premises & Equipment Control
- Quality Control and Good Laboratory Practice
- Complaints & Document Management
- Calibration and Warehousing
Topic wise notes of:
Medicinal Chemistry III
- Antibiotics & Aminoglycosides
- Antibiotics & Antimalarials: Structures & SAR
- Anti-TB, UTI & Antiviral Agents
- Antifungals, Antiprotozoals & Sulfonamides
- Intro to Drug Design & QSAR Approaches
Topic wise notes of:
Pharmaceutical Biotechnology
- Introduction to Pharmaceutical Biotechnology
- Genetic Engineering & rDNA Technology
- Immunology and Vaccine Technology
- Microbial Genetics & Biotransformation
- Fermentation & Bioproduct Production
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1. Drugs Acting on Respiratory System
a. Anti-asthmatic drugs
- Bronchodilators: β2 agonists (salbutamol), anticholinergics (ipratropium), methylxanthines (theophylline).
- Anti-inflammatory: Corticosteroids, leukotriene antagonists, mast cell stabilizers.
b. COPD drugs
- Long-acting bronchodilators (LABA, LAMA).
- Inhaled corticosteroids (severe cases).
- Phosphodiesterase-4 inhibitors.
c. Expectorants & Antitussives
- Expectorants: guaifenesin, potassium iodide (increase secretion).
- Antitussives: codeine, dextromethorphan (suppress cough reflex).
d. Nasal decongestants
- Sympathomimetics (oxymetazoline, pseudoephedrine). Reduce mucosal edema via vasoconstriction.
e. Respiratory stimulants
- Doxapram, nikethamide. Act on medullary centers to stimulate breathing.
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2. Drugs Acting on Gastrointestinal Tract
a. Antiulcer agents
- Antacids, H2 blockers (ranitidine), proton pump inhibitors (omeprazole), cytoprotectives.
b. Constipation & diarrhoea
- Laxatives: bulk (psyllium), stimulant (senna).
- Antidiarrheals: loperamide, ORS.
c. Appetite regulators
- Stimulants: corticosteroids, cyproheptadine.
- Suppressants: sibutramine (withdrawn), orlistat.
d. Digestants & carminatives
e. Emetics & antiemetics
- Emetics: apomorphine, ipecac.
- Antiemetics: ondansetron (5-HT3 blocker), metoclopramide, antihistamines
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