Phenidamine Tartrate is a piperazine-derived H₁-antihistamine used for the symptomatic treatment of allergic conditions such as rhinitis, urticaria, and cold-related discomforts. Its structure includes a diphenylmethyl group attached to a piperazine ring via an ethyl chain, and the tartrate salt enhances solubility.
Structure of Phenidamine Tartrate
- Phenidamine is a piperazine derivative with a diphenylmethyl substitution and an ethyl chain.
- It forms a salt with tartaric acid to improve solubility.
- Chemical Formula: C₁₄H₂₀N₂·C₄H₆O₆
Mode of Action
- Functions as an H₁-antagonist with anticholinergic properties.
- It blocks histamine receptors to alleviate allergic symptoms.
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Uses
- Allergic Reactions: Treats symptoms such as sneezing, itching, and runny nose.
- Urticaria: Alleviates hives and skin itching.
- Cold Symptoms: Helps reduce nasal congestion and other related symptoms.
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