Phenidamine Tartrate is a piperazine-derived H₁-antihistamine used for the symptomatic treatment of allergic conditions such as rhinitis, urticaria, and cold-related discomforts. Its structure includes a diphenylmethyl group attached to a piperazine ring via an ethyl chain, and the tartrate salt enhances solubility. By blocking histamine receptors and exhibiting anticholinergic activity, Phenidamine effectively reduces symptoms like sneezing, itching, and nasal congestion.
Structure of Phenidamine Tartrate
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- Phenidamine is a piperazine derivative with a diphenylmethyl substitution and an ethyl chain.
- It forms a salt with tartaric acid to improve solubility.
- Chemical Formula: C₁₄H₂₀N₂·C₄H₆O₆
Mode of Action
- Functions as an H₁-antagonist with anticholinergic properties.
- It blocks histamine receptors to alleviate allergic symptoms.
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Uses
- Allergic Reactions: Treats symptoms such as sneezing, itching, and runny nose.
- Urticaria: Alleviates hives and skin itching.
- Cold Symptoms: Helps reduce nasal congestion and other related symptoms.
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