Toxicology Basics & Chrono pharmacology Notes [U-5]
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Principles of toxicology
- Principles of Toxicology
- Acute toxicity
- Subacute toxicity
- Chronic Toxicity
- Genotoxicity
- Carcinogenicity
- Teratogenicity
- Mutagenicity
- General principles of treatment of poisoning
Clinical Symptoms and Management of Specific Poisonings
- Barbiturates Poisoning
- Morphine (Opioid) Poisoning
- Organophosphorus (OP) Compound Poisoning
Heavy Metals Poisoning: Lead, Mercury, and Arsenic
- Lead Poisoning
- Mercury Poisoning
- Arsenic Poisoning
Chrono pharmacology
- Chronopharmacology
- Rhythms and Cycles in Chronopharmacology
- Biological Clock and Its Significance
- Chronotherapy
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Other Units of Pharmaceutical Quality Assurance
Pharmacology III
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Other Subjects of B Pharmacy 6th Semester
Topic wise notes of:
Biopharmaceutics and Pharmacokinetics
- Biopharmaceutics: Absorption & Distribution
- Drug Elimination, Bioavailability & Bioequivalence
- Pharmacokinetics Models, Dosing & Parameters
- Multicompartment models
- Nonlinear Pharmacokinetics
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Topic wise notes of:
Pharmaceutical Quality Assurance
- Quality Assurance, GMP, ICH, QbD & Quality System
- GMP: Personnel, Premises & Equipment Control
- Quality Control and Good Laboratory Practice
- Complaints & Document Management
- Calibration and Warehousing
Topic wise notes of:
Medicinal Chemistry III
- Antibiotics & Aminoglycosides
- Antibiotics & Antimalarials: Structures & SAR
- Anti-TB, UTI & Antiviral Agents
- Antifungals, Antiprotozoals & Sulfonamides
- Intro to Drug Design & QSAR Approaches
Topic wise notes of:
Pharmaceutical Biotechnology
- Introduction to Pharmaceutical Biotechnology
- Genetic Engineering & rDNA Technology
- Immunology and Vaccine Technology
- Microbial Genetics & Biotransformation
- Fermentation & Bioproduct Production
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Toxicology Notes Summary
- Toxicity types:
- Acute: Single/short exposure.
- Subacute: Repeated weeks.
- Chronic: Long-term low dose.
- Special toxicities:
- Treatment principles: Prevent absorption, enhance elimination, use antidotes, supportive care.
- Specific poisons:
- Barbiturates → CNS depression; alkaline diuresis.
- Morphine → Naloxone.
- Organophosphates → Atropine, Pralidoxime.
- Lead, Mercury, Arsenic → Chelation therapy.
Chrono pharmacology Notes Summary
- Rhythms: Circadian, ultradian, infradian cycles.
- Biological clock: Regulates physiology and drug response.
- Chronotherapy: Time-based drug dosing for better efficacy and lower toxicity.
At FirstHope, we provide BPharm notes that are topic-wise, easy to understand, and designed strictly as per the AKTU and Other Universities, hence designed according to PCI syllabus.
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