Concept of Reduction is a process in which a chemical species gains one or more electrons, leading to a decrease in its oxidation state. In other words, the species becomes less positively charged or more negatively charged. Reduction is often associated with the addition of hydrogen to a substance or the removal of oxygen from it, … Read more
Concept of Oxidation is a process in which a chemical species loses one or more electrons, leading to an increase in its oxidation state. In simpler terms, the species becomes more positively charged. Oxidation is often associated with the addition of oxygen to a substance or the removal of hydrogen from it. However, the key factor … Read more
In this Introduction to Redox Titrations, a form of volumetric analysis, are widely used in pharmaceutical analysis to determine the concentration of substances via oxidation-reduction reactions. These titrations play a key role in ensuring the quality, safety, and potency of drug substances and products. Principles of Redox Titration Redox Reaction: Redox titration is based on … Read more
Ideal characteristics of tablets include uniform weight, hardness, and resistance to chipping, ensuring consistent quality and durability. Ideal characteristics of tablets involve rapid disintegration, accurate dosage, and high bioavailability for effective therapeutic action. An ideal tablet should possess the following features: Physical Properties: Uniform weight, size, and shape. Smooth surface with no cracks or chips. … Read more
Introduction to Tablet: Made by compression, widely used for systemic and local effects. Introduction to Tablet: Solid oral dosage form with precise drug dose, easy to use and transport. Tablets are solid dosage forms containing active pharmaceutical ingredients (APIs) and excipients, intended for oral administration. They are the most commonly used form of drug delivery … Read more
Oxidative phosphorylation represents the culmination of energy-producing metabolic pathways in eukaryotic cells, such as glycolysis, the citric acid cycle, and fatty acid oxidation. It occurs in the inner membrane of mitochondria, where it harnesses the energy released from electron transfer to synthesize adenosine triphosphate (ATP), the primary energy currency of the cell. This process involves … Read more
The Electron Transport Chain (ETC), located in the inner mitochondrial membrane, is the final phase of cellular respiration and a key step in ATP production through oxidative phosphorylation. ETC involves a series of protein complexes and electron carriers that transfer electrons from NADH and FADH2 to molecular oxygen, creating a proton gradient that drives ATP … Read more
Biological oxidation refers to the process by which living organisms extract energy from organic molecules, playing a critical role in metabolism. It involves the controlled release of energy to form ATP (adenosine triphosphate), the primary energy currency of the cell. This process occurs through interconnected pathways like glycolysis, the citric acid cycle, and oxidative phosphorylation, … Read more
Blood glucose levels are tightly regulated by hormones, mainly insulin and glucagon, to ensure a stable energy supply. Dysregulation of this system can lead to diabetes mellitus, characterized by prolonged hyperglycemia. Hormonal Regulation of Blood Glucose Insulin of Blood glucose: Produced by: Beta cells of the pancreas. Released in response to: High glucose (after meals). … Read more
Glycogen metabolism is a vital process in the human body, responsible for the storage and release of glucose, which is a primary source of energy. This process includes two main pathways: glycogenesis (the synthesis of glycogen) and glycogenolysis (the breakdown of glycogen). Abnormalities in these processes can lead to glycogen storage diseases (GSD), a group … Read more
