Busulfan is an anti-neoplastic alkylating agent used mainly in chronic myeloid leukemia (CML) by suppressing bone marrow and inhibiting cancer cell growth. Structure of Busulfan Busulfan is a bifunctional alkylating agent with two chloroethyl groups attached to a sulfur atom. Chemical Formula: C₄H₈Cl₂NS Mode of Action DNA Alkylation: Forms interstrand and intrastrand crosslinks with DNA, … Read more
General Introduction to Carotenoids (Other Terpenoids): Carotenoids are tetraterpenoids responsible for the yellow, orange, and red colors in plants. They are precursors of vitamin A and have antioxidant properties. Synonyms: Common name: Carotenoids Examples: Beta-carotene, Lycopene, Lutein Biological Source: Found in carrots (Daucus carota), tomatoes (Solanum lycopersicum), and marigold flowers (Tagetes erecta). Family: Varies depending … Read more
General Introduction to Taxus (Diterpenoids): Taxus (Yew tree) is a source of the diterpenoid paclitaxel, a potent anticancer agent. Synonyms: Common name: Yew Scientific name: Taxus brevifolia, Taxus baccata Synonyms: Pacific Yew, European Yew Biological Source: Derived from the bark of Taxus brevifolia and needles of Taxus baccata. Family: Taxaceae Composition: Major diterpenoid: Paclitaxel (Taxol): … Read more
General Introduction to Artemisia (Terpenoids): Artemisia contains sesquiterpene lactones, notably artemisinin, which is used in the treatment of malaria. Synonyms: Common name: Wormwood Scientific name: Artemisia annua Synonyms: Qinghao (Chinese) Biological Source: Derived from the aerial parts of Artemisia annua. Family: Asteraceae Composition: Major terpenoids: Artemisinin: A sesquiterpene lactone. Other sesquiterpenes and monoterpenes. Chemistry & … Read more
General Introduction to Gentian (Iridoids): Gentian (Iridoids) is a bitter tonic herb used to stimulate appetite and digestion. Its bitterness is attributed to iridoid glycosides. Synonyms: Common name: Gentian Scientific name: Gentiana lutea Synonyms: Yellow Gentian Biological Source of: Derived from the roots and rhizomes of Gentiana lutea. Family: Gentianaceae Composition: Major iridoid glycosides: Gentiopicroside … Read more
Introduction to Iridoids, Other Terpenoids & Naphthoquinones: Plant-based bioactive compounds. Introduction to Iridoids, Other Terpenoids & Naphthoquinones: Known for anti-inflammatory and antimicrobial roles. Iridoids: Structure: Derived from monoterpenes with a cyclopentane[c]pyran ring, often occurring as glycosides hydrolyzed to release active aglycones. Plant Functions: Serve as defense compounds (bitter and toxic), aid in signaling, and deter … Read more
General Introduction to Bitter Almond (Cyanogenic Glycosides): Bitter almond contains cyanogenic glycosides that release hydrocyanic acid upon enzymatic hydrolysis. It is used in small amounts for its flavoring and therapeutic effects but is toxic in high doses. Synonyms of Bitter Almond (Cyanogenic Glycoside): Common name: Bitter Almond Scientific name: Prunus amygdalus var. amara Synonyms: Amygdalin, … Read more
General Introduction to Aloes (Anthraquinone Glycosides): Aloes are rich in anthraquinone glycosides and are used as laxatives and wound-healing agents. Aloe gel is widely used in cosmetics and skin care products. Synonyms of Aloes (Anthraquinone Glycoside): Common name: Aloe Scientific name: Aloe barbadensis, Aloe ferox Synonyms: Ghritkumari (Hindi), Cape Aloe, Curacao Aloe Biological Source: Derived … Read more
General Introduction to Senna (Anthraquinone Glycosides): Senna contains anthraquinone glycosides, which are widely used as stimulant laxatives. The plant is recognized for its purgative effect on the gastrointestinal system. Synonyms of Senna (Anthraquinone Glycoside): Common name: Senna Scientific name: Cassia angustifolia, Cassia acutifolia Synonyms: Indian Senna, Tinnevelly Senna, Alexandrian Senna Biological Source: Derived from the … Read more
Introduction to Glycosides: Glycosides are bioactive compounds where a sugar (glycone) is bonded to a non-sugar (aglycone). They are widely found in plants and used for therapeutic, coloring, and flavoring properties. Definition & Structure of Glycoside: General Structure: Composed of a sugar (glycone) linked to a non-sugar moiety (aglycone) via a glycosidic bond. Diversity: The … Read more
