Month: August 2025

Prilocaine is an amide local anesthetic commonly used in dental and infiltration anesthesia with lower toxicity risk. Structure of Prilocaine Prilocaine is an amide-type local anesthetic with an isopropyl group attached to the diethylaminoethyl side chain, providing effective anesthetic properties with reduced toxicity. Chemical Formula: C₁₂H₂₈N₂O Mode of Action Voltage-Gated Sodium Channel Blockade: Inhibits sodium … Read more

Dibucaine is a potent amide local anesthetic used topically for pain relief and hemorrhoid treatment. Structure of Dibucaine It is a potent amino benzoic acid derivative with a butyl ester group, providing long-lasting local anesthetic effects. Chemical Formula: C₁₀H₂₀N₂O₂ Mode of Action Sodium Channel Blockade: Inhibits voltage-gated sodium channels, preventing nerve impulse conduction. Membrane Stabilization: … Read more

Diperodon is a local anesthetic applied topically in ophthalmology and dentistry to numb mucous membranes. Structure of Diperodon It is a synthetic amino benzoic acid derivative with a cyclohexylmethyl substituent, enhancing its local anesthetic potency. Chemical Formula: C₁₀H₂₀N₂O₂ Mode of Action Voltage-Gated Sodium Channel Inhibition: Blocks sodium influx, preventing nerve impulse transmission. Membrane Stabilization: Reduces … Read more

Phenacaine is an ester-type local anesthetic used mainly in ophthalmology for surface eye anesthesia. Structure of Phenacaine It is an amino benzoic acid derivative with a propyl ester group, providing effective local anesthetic properties. Chemical Formula: C₁₀H₂₀N₂O₂ Mode of Action Sodium Channel Blockade: Inhibits voltage-gated sodium channels, preventing nerve impulse conduction. Membrane Stabilization: Enhances nerve … Read more

Etidocaine is a long-acting amide local anesthetic used for surgical anesthesia and nerve blocks. Structure of Etidocaine It is an amide-type local anesthetic with an extended diethylaminoethyl side chain, providing prolonged anesthetic effects. Chemical Formula: C₁₅H₂₈N₂O Mode of Action Sodium Channel Inhibition: Blocks voltage-gated sodium channels, preventing nerve impulse propagation. Membrane Stabilization: Reduces nerve excitability … Read more

Mepivacaine is an amide local anesthetic used for infiltration and regional anesthesia with rapid onset and moderate duration. Structure of Mepivacaine It is an amide-type local anesthetic similar to lidocaine but with a methyl group attached to the diethylaminoethyl side chain, enhancing its potency. Chemical Formula: C₁₄H₂₈N₂O Mode of Action Sodium Channel Blockade: Blocks voltage-gated … Read more

Piperocaine is an ester-type local anesthetic used for infiltration and surface anesthesia by blocking nerve conduction. Structure of Piperocaine It is a synthetic local anesthetic with a piperidine ring attached to a benzamide core, enhancing its anesthetic potency and duration. Chemical Formula: C₁₀H₂₁N₃O Mode of Action Sodium Channel Inhibition: Blocks voltage-gated sodium channels, preventing nerve … Read more

Cyclomethycaine is an ester-type local anesthetic used for surface anesthesia by inhibiting nerve impulse transmission. Structure of Cyclomethycaine It is a synthetic local anesthetic with a cyclohexylmethyl substituent attached to a benzamide core. Chemical Formula: C₁₀H₁₈N₂O Mode of Action Voltage-Gated Sodium Channel Blockade: Prevents nerve impulse conduction by inhibiting sodium channels. Localized Action: Provides effective … Read more

Lignocaine (Lidocaine) is a widely used amide local anesthetic for infiltration, nerve blocks, and surface anesthesia. Structure of Lignocaine Lignocaine, commonly known as Lidocaine, is an amide-type local anesthetic with a diethylaminoethyl side chain attached to a 1,5-dimethyl-2-phenyl-4-imidazolidinone core. Chemical Formula: C₁₂H₂₁N₃O Mode of Action Voltage-Gated Sodium Channel Blockade: Inhibits sodium influx, preventing nerve impulse … Read more