Acetomenadione

Acetomenadione is a synthetic vitamin K derivative used as a coagulant to treat bleeding disorders from vitamin K deficiency.

Structure of Acetomenadione

  • Acetomenadione is a synthetic derivative of vitamin K, structurally similar to menadione with additional functional groups enhancing its activity.
  • Chemical Formula: C₁₂H₈O₃

Structure of Acetomenadione

Mode of Action

  • Provitamin K Activity: Acts as a precursor to active vitamin K forms.
  • Coagulation Factor Synthesis: Facilitates the carboxylation of clotting factors, promoting normal blood coagulation.
  • Antioxidant Effects: Provides free radical scavenging benefits.
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Uses

  • Vitamin K Deficiency: Manages bleeding disorders by restoring vitamin K levels.
  • Neonatal Coagulation Disorders: Prevents hemorrhagic disease of the newborn.
  • Research: Investigated for its role in coagulation and antioxidant mechanisms.

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