Acridine is a nitrogen heterocyclic compound used in dyes, antiseptics, and anticancer research in medicinal chemistry.
Chemical Formula of Acridine:
- C₁₃H₉N
Physical Properties of Acridine:
| Property | Value |
| Appearance | Yellow crystalline solid |
| Melting Point | ~110 °C |
| Boiling Point | ~345 °C |
| Solubility | Slightly soluble in water, soluble in ethanol and ether |
| Basicity | pKa ~5.5 |
Medicinal Uses:
- Used in antimalarial and antibacterial agents.
- Acridine dyes (e.g., acridine orange) used as DNA/RNA intercalating stains.
- Acts as a nucleic acid intercalator, which may be exploited for anticancer activity.
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