Energy-rich compounds are essential for cellular metabolism, acting as molecular energy stores and carriers. These compounds release significant energy upon breaking high-energy bonds, driving various biological processes. Key Energy-Rich Compounds Adenosine Triphosphate (ATP) Structure: Adenine base, ribose sugar, and three phosphate groups. Function: Primary cellular energy currency, providing energy for muscle contraction, active transport, and … Read more
Redox potential (Eh) is a measure of a chemical species’ tendency to gain (reduction) or lose (oxidation) electrons, crucial in biochemical energy transfer and electron transport processes. Basics of Redox Potential Definition: Indicates a molecule’s ability to accept (oxidizing agent) or donate (reducing agent) electrons. Expression: Measured in volts (V) or millivolts (mV) relative to … Read more
The relationship between free energy (G), enthalpy (H), and entropy (S) is fundamental in biochemistry, determining the spontaneity and direction of chemical reactions in biological systems. These relationship between free energy (G), enthalpy (H), and entropy (S)thermodynamic parameters are interconnected through the Gibbs free energy equation, which predicts reaction feasibility. Gibbs Free Energy Equation The relationship … Read more
Exergonic and endergonic reactions are two types of chemical processes classified by their energy changes. An exergonic reaction releases free energy to the surroundings, resulting in a negative ΔG (ΔG < 0). An endergonic reaction requires an input of free energy from the surroundings, resulting in a positive ΔG (ΔG > 0). 1. Exergonic Reactions … Read more
The legal process for manufacture of drugs for test examination and analysis under Indian drug laws and regulatory provisions. Manufacturing drugs for non-commercial purposes, such as testing, examination, and analysis, is allowed under specific conditions: Key Provisions: Purpose-Specific Manufacturing: Drugs must be used strictly for clinical trials, research, or quality analysis, not for commercial sale. … Read more
In bioenergetics, free energy refers to the portion of a system’s energy that is available to do work. The specific form of energy used to understand biological reactions is called Gibbs Energy (G). It helps predict whether a chemical reaction will occur spontaneously under constant temperature and pressure. Gibbs Energy (G) is defined by the … Read more
Understand the approval process and legal requirements for manufacture of new drug under Indian regulations and the Drugs and Cosmetics Act. Manufacture of New Drug The manufacture of new drugs—not previously approved or registered—requires stringent regulations to ensure safety and efficacy. Key Provisions: Clinical Trials: Comprehensive clinical trials are required to establish safety and efficacy, … Read more
This article explains the conditions for grant of manufacturing license under drug laws in India, including legal requirements and compliance rules. Obtaining a license to manufacture drugs in India involves adhering to specific conditions designed to maintain high manufacturing standards: Conditions for Grant of Manufacturing License Infrastructure and Facilities: Adequate manufacturing facilities, storage areas, and … Read more
Bioenergetics Introduction Bioenergetics Introduction: It is a critical subfield of biochemistry that focuses on understanding how living organisms acquire, transform, and use energy to sustain life. This complex process involves various biochemical reactions and pathways that convert energy from one form to another, enabling cells to perform essential functions such as growth, repair, movement, and … Read more
This topic explains about the prohibition of manufacture and sale of certain drugs in India, and the legal restrictions under the Drugs and Cosmetics Act. Prohibition of Manufacture and Sale of Certain Drugs The Act prohibits the manufacture and sale of specific categories of drugs to safeguard public health. Prohibited Drugs: Adulterated Drugs: Drugs containing … Read more
