Anti-Anginal Drugs

Anti-Anginal Drugs are medications that relieve chest pain in angina by improving blood flow to the heart or reducing its oxygen demand.

• Anti-anginal drugs are medications used to alleviate and prevent angina pectoris (chest pain) resulting from myocardial ischemia.
• They work by either increasing the oxygen supply to the heart muscle or decreasing its oxygen demand.
• Effective management of angina often involves a combination of these medications tailored to the patient’s specific needs.

Classification of Anti-Anginal Drugs:

1. Vasodilators (Nitrates):

   • Mechanism: These drugs relax blood vessels, increasing oxygen supply to the myocardium and reducing the workload on the heart.
   • Examples:
     • Amyl Nitrite
     • Nitroglycerin (common for acute angina relief)
     • Pentaerythritol tetranitrate
     • Isosorbide dinitrate
     • Dipyridamole

2. Calcium Channel Blockers:

   • Mechanism: These drugs prevent calcium from entering heart and blood vessel cells, leading to muscle relaxation, dilation of arteries, and improved blood flow.
   • Examples:
     • Verapamil
     • Bepridil hydrochloride
     • Diltiazem hydrochloride
     • Nifedipine
     • Amlodipine
     • Felodipine
     • Nicardipine
     • Nimodipine

Summary Table

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