Antipyrine

  • Antipyrine is used as an analgesic and antipyretic, often in ear preparations for pain relief.
  • It works by inhibiting prostaglandin synthesis, reducing pain, fever, and inflammation.

Chemical Formula:

  • C₁₁H₁₂N₂O

Chemical Structure of Antipyrine

Mechanism of Antipyrine:

  • COX inhibition
  • Also acts as antipyretic and analgesic

Uses of Antipyrine:

  • Historical use for fever, pain
  • Component in ear drop formulations today
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Side Effects:

  • Hypersensitivity
  • Agranulocytosis (rare)

Notes:

  • Older agent; rarely used systemically now

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