- Explore Aspirin (Acetylsalicylic acid) for pain relief, anti-inflammatory action, and cardiovascular protection.
- It works by inhibiting COX enzymes, reducing prostaglandin synthesis.
Chemical Formula:
- C₉H₈O₄
Mechanism of Aspirin (Acetylsalicylic acid):
- Irreversible inhibitor of COX-1 & COX-2
- Acetylates serine residue on COX enzymes
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Uses of Aspirin (Acetylsalicylic acid):
- Analgesic, antipyretic
- Anti-inflammatory (high dose)
- Anti-platelet (low dose)
Side Effects:
- GI bleeding/ulcers
- Tinnitus
- Reye’s syndrome in children
- Asthma exacerbation
Notes:
- Cardioprotective in low doses (81 mg daily)
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