- Atropine Sulfate treats bradycardia, reduces secretions, and acts as an antidote in organophosphate poisoning.
- Atropine Sulfate blocks muscarinic receptors, producing anticholinergic effects for smooth muscle relaxation and eye dilation.
Formula:
- (C₁₇H₂₃NO₃)₂·H₂SO₄
Mechanism of Atropine Sulfate:
- Competitive muscarinic receptor antagonist
- Affects M1–M5; especially heart (M2) and secretory tissues (M3)
Uses:
- Bradycardia
- Pre-anesthetic (reduce secretions)
- Organophosphate poisoning (alongside 2-PAM)
- Mydriasis & cycloplegia
Side Effects of Atropine Sulfate:
- Dry mouth
- Blurred vision
- Urinary retention
- Tachycardia
- CNS stimulation (high doses)
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