Azatidine Maleate is a first-generation H₁-antihistamine effective in treating allergic conditions such as rhinitis, urticaria, and cold symptoms. Its structure includes a tricyclic ring system fused to a pyridine ring, and it forms a salt with maleic acid to enhance solubility.
Structure of Azatidine Maleate
- Azatidine is a first-generation antihistamine with a tricyclic structure fused to a pyridine ring.
- It forms a salt with maleic acid to improve solubility.
- Chemical Formula: C₁₉H₂₇N₃·C₄H₄O₄
Mode of Action
- Acts as an H₁-receptor antagonist with anticholinergic and sedative effects.
- It inhibits histamine-mediated allergic responses.
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Uses
- Allergic Reactions: Treats symptoms such as sneezing, itching, and runny nose.
- Urticaria: Alleviates hives and skin itching.
- Cold Symptoms: Helps reduce nasal congestion and other related discomforts.
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