Anti-Anginal & Diuretics Notes [U-2]
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Anti-Anginal
- Angina Pectoris
- Anti-Anginal Drugs
Various vasodilators drugs
- Amyl Nitrite
- Nitroglycerin
- Pentaerythritol Tetranitrate
- Isosorbide Dinitrite
- Dipyridamole
Various Calcium Channel Blockers
- Verapamil
- Bepridil Hydrochloride
- Diltiazem Hydrochloride
- Nifedipine
- Amlodipine
- Felodipine
- Nicardipine
- Nimodipine
Diuretics
- Diuretics: Overview and Classification
Various Carbonic Anhydrase Inhibitors
- Acetazolamide
- Methazolamide
- Dichlorphenamide
Various Thiazides
- Chlorthiazide
- Hydrochlorothiazide
- Hydroflumethiazide
- Cyclothiazide
Various Loop Diuretics
- Furosemide
- Bumetanide
- Ethacrynic Acid
Various Potassium-Sparing Diuretics
- Spironolactone
- Triamterene
- Amiloride
Various Osmotic Diuretics
- Mannitol
Anti-Hypertensive Agents
- Hypertension
- Anti-Hypertensive Agents
Various Beta-Blockers
- Timolol
Various ACE Inhibitors
- Captopril
- Lisinopril
- Enalapril
- Benazepril Hydrochloride
- Quinapril Hydrochloride
Various Alpha-2 Agonists
- Methyldopate Hydrochloride
- Clonidine Hydrochloride
Various Sympatholytics
- Guanethidine Monosulphate
- Guanabenz Acetate
- Reserpine
Direct Vasodilators
- Sodium Nitroprusside
- Diazoxide
- Minoxidil
- Hydralazine Hydrochloride
Unit II Summary: Anti-Anginal, Diuretics, and Anti-Hypertensives
This unit explains medicines used in heart-related problems. To begin with, anti-anginal drugs help reduce chest pain. For example, vasodilators like Nitroglycerin*, Isosorbide dinitrate*, and Dipyridamole increase blood flow to the heart. Similarly, calcium channel blockers such as Amlodipine, Verapamil, and Diltiazem relax the heart muscles and lower blood pressure.
Next, let’s look at diuretics, which help remove extra water and salt from the body. There are different types. Firstly, carbonic anhydrase inhibitors like Acetazolamide* reduce fluid in the body. Secondly, thiazide diuretics such as Hydrochlorothiazide lower blood pressure effectively. Thirdly, loop diuretics like Furosemide* act fast and are used in emergencies. In contrast, potassium-sparing diuretics like Spironolactone help keep potassium in the body. Finally, osmotic diuretics like Mannitol are used to treat brain swelling.
After that, the unit discusses anti-hypertensive drugs. These are used to manage high blood pressure. Examples include beta-blockers like Timolol, ACE inhibitors like Captopril and Enalapril, and central-acting drugs such as Clonidine* and Methyldopa. Furthermore, vasodilators like Minoxidil and Sodium nitroprusside help relax blood vessels.
