Anti-Diabetic & Local Anaesthetic Agents Notes [U-5]
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Anti-Diabetic Agents
- Diabetes Mellitus
- Insulin
- Preparation of Insulin
- Antidiabetic agents
Various Sulfonylureas
- Tolbutamide
- Chlorpropamide
- Glipizide
- Glimepiride
Various Biguanides
- Metformin
Various Thiazolidinediones
- Pioglitazone
- Rosiglitazone
- Repaglinide
- Nateglinide
Various Glucosidase Inhibitors
- Acarbose
- Voglibose
Local Anaesthetics
- Local Anesthetics
- SAR of Local anaesthesia
- Classification of Local Anesthetics
Various Benzoic Acid Derivatives
- Cocaine
- Hexylcaine
- Meprylcaine
- Cyclomethycaine
- Piperocaine
Various Amino Benzoic Acid Derivatives
- Benzocaine
- Butamben
- Procaine
- Butacaine
- Propoxycaine
- Tetracaine
- Benoxinate
Lidocaine/Anilide Derivatives
- Lignocaine
- Mepivacaine
- Prilocaine
- Etidocaine
Miscellaneous
- Phenacaine
- Diperodon
- Dibucaine
Summary of Unit V: Anti-diabetic Agents and Local Anesthetics
Unit V focuses on two critical pharmacological categories: Antidiabetic agents and Local Anesthetics, providing concise and exam-focused content ideal for students preparing AKTU pharmacy notes, B Pharma notes, or competitive exams like GPAT and NIPER.
Antidiabetic agents include several drug classes essential for managing diabetes. These include:
- Insulin and its preparations
- Sulfonylureas such as Tolbutamide*, Chlorpropamide, Glipizide, and Glimepiride
- Biguanides like Metformin
- Thiazolidinediones including Pioglitazone and Rosiglitazone
- Meglitinides such as Repaglinide and Nateglinide
- Glucosidase inhibitors like Acarbose and Voglibose
Local Anesthetics are classified based on their chemical structures and SAR (Structure-Activity Relationship).
- Benzoic acid derivatives: Cocaine, Hexylcaine, Meprylcaine
- Amino benzoic acid derivatives: Benzocaine*, Procaine*, Butamben
- Anilide derivatives: Lidocaine, Mepivacaine, Prilocaine
- Miscellaneous: Phenacaine, Dibucaine
