Benztropine Mesylate

Chemical Formula:

  • C₂₁H₂₅NO·CH₄O₃S

 Chemical Structure of Benztropine Mesylate

Mechanism of Action:

  • Centrally acting M1 antagonist
  • Also has weak dopamine reuptake inhibition (antiparkinsonian effect)

Therapeutic Uses of Benztropine Mesylate:

  • Parkinson’s disease (adjunct)
  • Drug-induced extrapyramidal symptoms (EPS)
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Side Effects of Benztropine Mesylate:

  • Dry mouth
  • Constipation
  • Confusion (esp. elderly)
  • Tachycardia
  • Blurred vision

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