Bitolterol

  • Bitolterol is a synthetic beta-2 adrenergic agonist used as a bronchodilator to treat reversible obstructive airway conditions such as asthma and chronic obstructive pulmonary disease (COPD).
  • It is typically administered via inhalation and works by relaxing the smooth muscles in the airways, leading to bronchodilation and improved airflow.

Chemical Structure & Formula

  • Chemical Formula: C₂₁H₂₉NO₄
  • Structure:
  • Bitolterol Structure
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Mechanism of Action (Detailed)

  • Prodrug of colterol → Converts to active β2 agonist in the lungs.
  • Provides bronchodilation with a longer duration than salbutamol.

Side Effects of Bitolterol

  • Same as other β2 agonists: Tachycardia, tremors, hypokalemia.
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Clinical Uses of Bitolterol

  • Used for asthma & COPD but rarely prescribed now due to newer alternatives.

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