Butamben is an ester-type local anesthetic used topically for pain relief by blocking nerve signal transmission.
Structure of Butamben
- It is an amino benzoic acid derivative with a butyl ester group attached to the benzene ring, providing enhanced anesthetic properties.
- Chemical Formula: C₁₀H₁₉NO₂
Mode of Action
- Sodium Channel Blockade: Blocks nerve impulse transmission by inhibiting voltage-gated sodium channels.
- Membrane Permeabilization: Stabilizes nerve membranes, reducing excitability.
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Uses
- Topical Anesthesia: Applied to mucous membranes and skin for numbing before minor procedures.
- Ophthalmic Anesthesia: Used in eye surgeries for corneal numbing.
- Dental Preparations: Incorporated in gels and creams for dental applications.
Side Effects of Butamben
- Local Irritation: Redness and mild irritation at the application site.
- Allergic Reactions: Rare but possible in sensitive individuals.
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