B Pharmacy is a 4-year undergraduate program in India that provides comprehensive knowledge of drugs, healthcare, and pharmaceutical sciences. It prepares students for careers in the pharmaceutical industry, clinical research, and healthcare services.
This course builds a strong foundation for B Pharmacy Students all over the world.
Butacaine is an ester-type local anesthetic used for surface anesthesia by blocking nerve conduction and providing temporary numbness. Structure of Butacaine It is an amino benzoic acid derivative with a butyl ester group, providing effective local anesthetic properties. Chemical Formula: C₁₀H₂₁N₃O₂ Mode of Action Sodium Channel Blockade: Inhibits voltage-gated sodium channels, preventing nerve impulse propagation. … Read more
Procaine is an ester-type local anesthetic used for infiltration and nerve block anesthesia by blocking nerve impulse conduction. Structure of Procaine Procaine is a classic amino benzoic acid derivative with an ethyl ester group, enhancing its solubility and anesthetic duration. Chemical Formula: C₁₀H₂₁N₃O₂ Mode of Action Voltage-Gated Sodium Channel Inhibition: Blocks sodium influx, preventing nerve … Read more
Butamben is an ester-type local anesthetic used topically for pain relief by blocking nerve signal transmission. Structure of Butamben It is an amino benzoic acid derivative with a butyl ester group attached to the benzene ring, providing enhanced anesthetic properties. Chemical Formula: C₁₀H₁₉NO₂ Mode of Action Sodium Channel Blockade: Blocks nerve impulse transmission by inhibiting … Read more
Benzocaine is an ester-type local anesthetic commonly used topically to relieve pain and itching by blocking nerve signals. Structure of Benzocaine Benzocaine is a simple amino benzoic acid derivative with a diethylamino group attached to the benzene ring, enhancing its lipophilicity and anesthetic properties. Chemical Formula: C₇H₉NO₂ Mode of Action Sodium Channel Blockade: Inhibits voltage-gated … Read more
Meprylcaine is an ester-type local anesthetic that provides surface and infiltration anesthesia by blocking nerve impulse conduction. Structure of Meprylcaine It is a synthetic local anesthetic with a diethylaminoethyl substituent attached to a benzamide core. Chemical Formula: C₁₁H₂₂N₂O Mode of Action Sodium Channel Blockade: Inhibits nerve impulse transmission by blocking voltage-gated sodium channels. Extended Duration: … Read more
Hexylcaine is an ester-type local anesthetic used for surface anesthesia by blocking nerve impulse conduction. Structure of Hexylcaine It is a synthetic local anesthetic with a benzocaine-like structure, featuring a hexyl ester group attached to a benzoic acid core. Chemical Formula: C₁₀H₁₇NO₂ Mode of Action Sodium Channel Inhibition: Blocks nerve impulse conduction by inhibiting voltage-gated … Read more
Cocaine is a natural ester local anesthetic that blocks nerve conduction and is also known for its stimulant and addictive properties. Structure of Cocaine It is a naturally occurring local anesthetic derived from the coca plant, featuring a tropane ring system with a benzoyl and methyl ester substituent. Chemical Formula: C₁₇H₂₃NO₄ Mode of Action Sodium … Read more
Classification of Local Anesthetics is based on their chemical structure, mainly ester-linked and amide-linked agents, with differing duration and use. Classification of Local Anesthetics Local anesthetics are categorized based on their chemical structure. Each class shares a common mechanism of action, primarily involving the inhibition of nerve impulse transmission. Below is the classification along with … Read more
Local anesthetics are drugs that block nerve conduction at the site of administration, causing temporary loss of sensation without unconsciousness. Definition: Local anesthetics are medications that temporarily block sensation in a specific area of the body without affecting consciousness. They are commonly used during surgical, dental, and diagnostic procedures to prevent or relieve pain. Mechanism … Read more
SAR of Local anaesthesia SAR of Local Anaesthesia shows how lipophilic group, intermediate chain, and amine group influence potency, duration, and activity. Aromatic Group (Lipophilic End): Typically, a benzene ring, responsible for lipophilicity, enabling penetration of nerve cell membranes. Potency is proportional to lipid solubility, influencing membrane penetration. Intermediate Chain (Linker): Connects the aromatic group … Read more
