B Pharmacy is a 4-year undergraduate program in India that provides comprehensive knowledge of drugs, healthcare, and pharmaceutical sciences. It prepares students for careers in the pharmaceutical industry, clinical research, and healthcare services.
This course builds a strong foundation for B Pharmacy Students all over the world.
Protein binding refers to the reversible association of a molecule, typically a drug or other bioactive compound, with one or more proteins in the body. T he most common proteins involved in this process are plasma proteins, such as albumin, α1-acid glycoprotein, and lipoproteins. It is binding can significantly impact the pharmacokinetics and pharmacodynamics of … Read more
Methods of Analysis for Complexes analysis explores the formation, stoichiometry, and stability of complexes between a central atom (typically a metal ion) and ligands. This understanding is essential in fields like chemistry, pharmacology, and materials science. Below are four primary methods used to analyze complexation: 1. Method of Continuous Variation (Job’s Method) Overview: Job’s Method determines … Read more
Applications of Complexation plays a crucial role in various scientific and industrial applications: 1. Pharmaceuticals Applications of Complexation Drug Delivery: Complexes can enhance the solubility, stability, and bioavailability of drugs. Metal-based Drugs: Complexes like cisplatin are used in cancer therapy. 2. Analytical Chemistry Applications of Complexation Titration: Complexometric titrations use complexes to determine metal ion concentrations … Read more
The classification of complexation, as shown in the image, is structured into three main categories. Here’s a detailed explanation: 1. Metal Ion Complexes/Coordinate Complexes These are complexes formed by metal ions binding with various ligands. This category includes: Inorganic Type: These complexes involve metal ions forming bonds with inorganic ligands. Chelates: A specific type of … Read more
Complexation and Protein Binding involve the reversible interaction of a drug with proteins or other molecules, forming complexes that affect the drug’s distribution, activity, and elimination. Complexation Introduction Complexation is a chemical process where molecules or ions combine to form a stable complex. It typically involves: Central Metal Ion: Usually a metal (e.g., Fe, Cu, … Read more
Alkyl halides, also known as haloalkanes or halogenoalkanes, are organic compounds containing one or more halogen atoms (fluorine, chlorine, bromine, or iodine) bonded to carbon atoms within an alkyl group. They are versatile compounds with various industrial, pharmaceutical, and laboratory applications. Types and Classification Alkyl halides can be classified based on two main criteria: the … Read more
Measurement of Surface can be measured using various techniques, each based on different physical principles. Below are the commonly used methods: 1. Capillary Rise Method for Measurement of Surface and Interfacial Tensions Principle: This method relies on the height a liquid rises in a capillary tube due to surface tension. The liquid rises because of adhesive … Read more
Definition of Hydrophile-Lipophile Balance Scale The HLB scale is a numerical system that indicates the balance between the hydrophilic and lipophilic portions of a surfactant molecule. Scale Range: 0 (completely lipophilic) to 20 (completely hydrophilic). Calculation of Hydrophile-Lipophile Balance Scale For nonionic surfactants: $\text{HLB} = 20 \times \frac{M_{\text{hydrophilic}}}{M_{\text{total}}}$ where: is the molecular mass of the … Read more
Definition of Adsorption at Solid Interfaces Adsorptions at solid interfaces involves the accumulation of molecules from a liquid or gas onto a solid surface. Types of Adsorption: Physical Adsorption (Physisorption) Forces: Weak van der Waals forces; reversible. Characteristics: Occurs at low temperatures; decreases with heat. Forms multilayers as molecules are loosely held. Example: Adsorption of … Read more
Definition of Detergency Detergency is the process by which surfactants clean surfaces by removing dirt, oils, and other contaminants. Mechanism Wetting: Surfactants lower surface tension, allowing cleaning solutions to spread. Emulsification: Oils and greases are emulsified and suspended. Dispersion: Particulate soils are dispersed and prevented from re-deposition. Factors Influencing Detergency Surfactant Concentration: Must be above … Read more
