Felodipine

Felodipine

Felodipine is a calcium channel blocker that treats high blood pressure and angina by relaxing blood vessels and lowering heart workload. Structure of Felodipine Felodipine is a dihydropyridine calcium channel blocker with a substituted phenyl ring and a methoxyethyl side chain attached to the dihydropyridine core. Chemical Formula: C₂₂H₂₄N₂O₅ Mode of Action Calcium Channel Blocking: … Read more

Amlodipine

Amlodipine

Amlodipine is a long-acting calcium channel blocker used in angina and hypertension by relaxing blood vessels and lowering heart workload. Structure of Amlodipine Amlodipine is a dihydropyridine calcium channel blocker with a substituted phenyl ring and an ethyl group attached to the dihydropyridine core. Chemical Formula: C₂₀H₂₄N₂O₅ Mode of Action Calcium Channel Blocking: Inhibits L-type … Read more

Bepridil Hydrochloride

Bepridil Hydrochloride

Bepridil Hydrochloride is a calcium channel blocker used in angina to reduce heart workload and improve coronary blood flow. Structure of Bepridil Hydrochloride It is a benzothiazepine derivative with a phenyl ring attached to a thiazepine ring containing multiple substituents. Chemical Formula: C₂₅H₃₈ClN₃OS Mode of Action Calcium Channel Blocking: Inhibits L-type calcium channels in cardiac … Read more

Diltiazem Hydrochloride

Diltiazem Hydrochloride

Diltiazem Hydrochloride is a calcium channel blocker used in angina to relax blood vessels and lower heart rate, reducing oxygen demand. Structure of Diltiazem Hydrochloride It is a benzothiazepine derivative with an imidazole ring fused to a thiazepine ring, attached to methoxy and ethyl substituents. Chemical Formula: C₂₀H₂₄N₂O₄S·HCl Mode of Action Calcium Channel Blocking: Inhibits … Read more

Nifedipine

Nifedipine

Nifedipine is a calcium channel blocker used in angina and hypertension by dilating blood vessels and reducing cardiac workload. Structure of Nifedipine Nifedipine is a dihydropyridine derivative featuring a phenyl ring attached to a dihydropyridine core with ethyl and methoxy substituents. Chemical Formula: C₁₅H₁₈N₂O₆ Mode of Action Calcium Channel Blocking: Selectively inhibits L-type calcium channels … Read more

Hematinics

Hematinics

Definition of Hematinics: Hematinics are agents that improve the hemoglobin content of the blood, thereby enhancing oxygen-carrying capacity. They are primarily used to treat anemia. Some Major Hematinic Agents:  1. Iron Preparations: Ferrous Sulfate, Ferrous Gluconate: Mechanism: Supply elemental iron for hemoglobin synthesis. Use: Iron deficiency anemia. Side Effects: Gastrointestinal upset, dark stools. Iron Sucrose, … Read more

Anemia

Definition of Anemia Anemia is a condition with decreased red blood cells (RBCs) or hemoglobin (Hb), reducing oxygen-carrying capacity and causing fatigue, weakness, and dyspnea. Types of Anemia Based on RBC Size (MCV): Microcytic (MCV < 80 fL): Iron deficiency, thalassemia, sideroblastic anemia. Normocytic (MCV 80–100 fL): Acute blood loss, chronic disease, hemolysis. Macrocytic (MCV … Read more

Drugs Used in the Therapy of Shock

Drugs Used in the Therapy of Shock

This article explains the Drugs Used in the Therapy of Shock such as vasopressors, inotropes, and fluids for emergency care. Drugs Used in the Therapy of Shock help restore blood pressure, perfusion, and organ function in critical conditions. Shock is a critical condition characterized by inadequate tissue perfusion and oxygenation, leading to cellular dysfunction and … Read more

Shock

Shock

Shock It is a life-threatening condition where inadequate tissue perfusion leads to cellular dysfunction, organ failure, and death if not promptly treated. Pathophysiology Initial Stage – Compensatory mechanisms (tachycardia, vasoconstriction) maintain perfusion. Progressive Stage – Oxygen delivery fails → Anaerobic metabolism → Lactic acidosis → Cell dysfunction. Irreversible Stage – Multi-organ failure → Death if … Read more

Dipyridamole

Dipyridamole

Dipyridamole is an anti-anginal and antiplatelet drug that improves coronary blood flow and prevents blood clots. Structure of Dipyridamole Dipyridamole is a bis(pyrrolidine) derivative linked by a central ethylene bridge with two methanol side groups. Chemical Formula: C₂₀H₂₂N₄O₂ Mode of Action Phosphodiesterase Inhibition: Inhibits the enzyme responsible for breaking down cyclic AMP and cyclic GMP, … Read more