B Pharmacy is a 4-year undergraduate program in India that provides comprehensive knowledge of drugs, healthcare, and pharmaceutical sciences. It prepares students for careers in the pharmaceutical industry, clinical research, and healthcare services.
This course builds a strong foundation for B Pharmacy Students all over the world.
Tezosentan is an endothelin receptor antagonist used in heart failure to improve blood flow and reduce vascular resistance. Structure of Tezosentan Tezosentan is a selective endothelin receptor antagonist with a quinazoline core linked to aromatic substituents and amine groups. Chemical Formula: C₂₄H₂₂N₄O₆S₂ Mode of Action Selective Endothelin Receptor Blocking: Primarily antagonizes ETA receptors, reducing vasoconstriction … Read more
Digitoxin is a cardiac glycoside that treats CHF by improving heart pumping efficiency and controlling heartbeat. Structure of Digitoxin Digitoxin is a cardiac glycoside similar to digoxin but with a longer half-life due to fewer hydroxyl groups on the steroid nucleus. Chemical Formula: C₄₉H₇₄O₁₉ Mode of Action Na⁺/K⁺-ATPase Inhibition: Similar to digoxin, inhibits the sodium-potassium … Read more
Digoxin is a cardiac glycoside used in CHF and atrial fibrillation to strengthen heart contractions and regulate rhythm. Structure of Digoxin Digoxin is a cardiac glycoside derived from the foxglove plant, featuring a steroid nucleus linked to a lactone ring and a sugar moiety. Chemical Formula: C₄₈H₇₂O₁₉ Mode of Action Na⁺/K⁺-ATPase Inhibition: Binds to the … Read more
Drugs used in congestive heart failure (CHF) aim to improve cardiac function, reduce symptoms, and enhance survival by targeting various physiological pathways involved in heart failure. Pathophysiology of Congestive Heart Failure CHF results from the heart’s inability to pump sufficient blood to meet the body’s needs. It involves complex mechanisms, including neurohormonal activation (e.g., renin-angiotensin-aldosterone … Read more
Congestive Heart Failure (CHF) is a chronic condition where the heart is unable to pump blood effectively to meet the body’s needs, leading to a buildup of fluid in tissues and organs. Types of Congestive Heart Failure (CHF): Left-Sided Heart Failure: Affects the left ventricle, causing fluid to back up into the lungs (pulmonary congestion). … Read more
Clopidogrel is an antiplatelet drug that prevents strokes and heart attacks by inhibiting platelet aggregation. Structure of Clopidogrel Clopidogrel is a thienopyridine class antiplatelet agent featuring a thiophene ring attached to a pyridine moiety with a chlorophenyl group. Chemical Formula: C₁₅H₁₂ClNO₂S Mode of Action P2Y₁₂ Receptor Inhibition: Irreversibly blocks the P2Y₁₂ ADP receptor on platelet … Read more
Anisindione is an oral anticoagulant that prevents blood clots by inhibiting vitamin K–dependent clotting factor synthesis. Structure of Anisindione It is a synthetic derivative of indione with aromatic substitutions enhancing its anticoagulant properties. Chemical Formula: C₁₅H₁₅NO₄S Mode of Action Vitamin K Epoxide Reductase Inhibition: Similar to warfarin, anisindione inhibits the enzyme responsible for regenerating reduced … Read more
Acetomenadione is a synthetic vitamin K derivative used as a coagulant to treat bleeding disorders from vitamin K deficiency. Structure of Acetomenadione Acetomenadione is a synthetic derivative of vitamin K, structurally similar to menadione with additional functional groups enhancing its activity. Chemical Formula: C₁₂H₈O₃ Mode of Action Provitamin K Activity: Acts as a precursor to … Read more
Warfarin is an oral anticoagulant that prevents blood clots by inhibiting vitamin K–dependent clotting factor synthesis. Structure of Warfarin Warfarin is a synthetic coumarin derivative with a 4-hydroxycoumarin core structure substituted with a 3-phenylpropyl side chain. Chemical Formula: C₁₉H₁₆O₄ Mode of Action Vitamin K Epoxide Reductase Inhibition: Blocks the enzyme vitamin K epoxide reductase, preventing … Read more
Menadione is a synthetic vitamin K used as a coagulant to treat and prevent bleeding caused by vitamin K deficiency. Structure of Menadione Menadione, also known as vitamin K3, is a synthetic compound with a naphthoquinone structure. Chemical Formula: C₁₀H₆O₂ Mode of Action Provitamin K Activity: Serves as a precursor to active vitamin K forms. … Read more
