B Pharmacy is a 4-year undergraduate program in India that provides comprehensive knowledge of drugs, healthcare, and pharmaceutical sciences. It prepares students for careers in the pharmaceutical industry, clinical research, and healthcare services.
This course builds a strong foundation for B Pharmacy Students all over the world.
Cytarabine is an anti-neoplastic antimetabolite used in leukemia treatment by inhibiting DNA synthesis in rapidly dividing cancer cells. Structure of Cytarabine It is also known as Ara-C, is a pyrimidine analog with the following structural features: Cytosine Base: Similar to the natural nucleobase cytosine. Ribose Sugar: Modified with an arabinose moiety. Chemical Formula: C₄H₇N₃O₅ Mode … Read more
Floxuridine is an anti-neoplastic antimetabolite used mainly in colorectal cancer by inhibiting DNA synthesis in tumor cells. Structure of Floxuridine FUDR is a fluorinated pyrimidine analog with the following structural features: Uracil Base: Similar to uracil. Fluorine Atom: Substituted at the 5-position. Ribose Sugar: Attached to the uracil base, forming a nucleoside. Chemical Formula: C₆H₆FN₂O₆ … Read more
Azathioprine is an immunosuppressive and anti-neoplastic agent used in autoimmune diseases and organ transplants by inhibiting DNA synthesis. Structure of Azathioprine Azathioprine is a prodrug of 6-mercaptopurine and contains the following structural features: Imidazole Ring: Attached to a purine analog. Mercaptopurine Moiety: Linked via a thioester bond. Chemical Formula: C₉H₁₃N₇O₃S Mode of Action Azathioprine acts … Read more
Fluorouracil is an anti-neoplastic antimetabolite used to treat cancers like colorectal and breast by blocking DNA synthesis in rapidly dividing cells. Structure of Fluorouracil It is a pyrimidine analog with the following structural features: Uracil Base: Similar to the natural nucleobase uracil. Fluorine Atom: Substituted at the 5-position. Chemical Formula: C₄H₃FN₂O₂ Mode of Action Fluorouracil … Read more
Thiotepa is an anti-neoplastic alkylating agent used to treat breast, ovarian, and bladder cancers by disrupting cancer cell DNA replication. Structure of Thiotepa Thiotepa is a trivalent phosphoramide alkylating agent containing three chloroethyl groups attached to a nitrogen atom. Chemical Formula: C₆H₁₃Cl₃N₄O₂P Mode of Action DNA Alkylation: Forms crosslinks within and between DNA strands, inhibiting … Read more
Definition of Terpenoids: Terpenoids, or isoprenoids, are a diverse class of naturally occurring organic compounds derived from five-carbon isoprene units. They undergo modifications like oxidation and rearrangement, resulting in varied structures and functions. Structure and Classification of Terpenoids: Based on isoprene units: Monoterpenoids: C₁₀ (2 units) Sesquiterpenoids: C₁₅ (3 units) Diterpenoids: C₂₀ (4 units) Triterpenoids: … Read more
Busulfan is an anti-neoplastic alkylating agent used mainly in chronic myeloid leukemia (CML) by suppressing bone marrow and inhibiting cancer cell growth. Structure of Busulfan Busulfan is a bifunctional alkylating agent with two chloroethyl groups attached to a sulfur atom. Chemical Formula: C₄H₈Cl₂NS Mode of Action DNA Alkylation: Forms interstrand and intrastrand crosslinks with DNA, … Read more
General Introduction to Carotenoids (Other Terpenoids): Carotenoids are tetraterpenoids responsible for the yellow, orange, and red colors in plants. They are precursors of vitamin A and have antioxidant properties. Synonyms: Common name: Carotenoids Examples: Beta-carotene, Lycopene, Lutein Biological Source: Found in carrots (Daucus carota), tomatoes (Solanum lycopersicum), and marigold flowers (Tagetes erecta). Family: Varies depending … Read more
General Introduction to Taxus (Diterpenoids): Taxus (Yew tree) is a source of the diterpenoid paclitaxel, a potent anticancer agent. Synonyms: Common name: Yew Scientific name: Taxus brevifolia, Taxus baccata Synonyms: Pacific Yew, European Yew Biological Source: Derived from the bark of Taxus brevifolia and needles of Taxus baccata. Family: Taxaceae Composition: Major diterpenoid: Paclitaxel (Taxol): … Read more
General Introduction to Artemisia (Terpenoids): Artemisia contains sesquiterpene lactones, notably artemisinin, which is used in the treatment of malaria. Synonyms: Common name: Wormwood Scientific name: Artemisia annua Synonyms: Qinghao (Chinese) Biological Source: Derived from the aerial parts of Artemisia annua. Family: Asteraceae Composition: Major terpenoids: Artemisinin: A sesquiterpene lactone. Other sesquiterpenes and monoterpenes. Chemistry & … Read more
