B Pharmacy is a 4-year undergraduate program in India that provides comprehensive knowledge of drugs, healthcare, and pharmaceutical sciences. It prepares students for careers in the pharmaceutical industry, clinical research, and healthcare services.
This course builds a strong foundation for B Pharmacy Students all over the world.
Acetomenadione is a synthetic vitamin K derivative used as a coagulant to treat bleeding disorders from vitamin K deficiency. Structure of Acetomenadione Acetomenadione is a synthetic derivative of vitamin K, structurally similar to menadione with additional functional groups enhancing its activity. Chemical Formula: C₁₂H₈O₃ Mode of Action Provitamin K Activity: Acts as a precursor to … Read more
Warfarin is an oral anticoagulant that prevents blood clots by inhibiting vitamin K–dependent clotting factor synthesis. Structure of Warfarin Warfarin is a synthetic coumarin derivative with a 4-hydroxycoumarin core structure substituted with a 3-phenylpropyl side chain. Chemical Formula: C₁₉H₁₆O₄ Mode of Action Vitamin K Epoxide Reductase Inhibition: Blocks the enzyme vitamin K epoxide reductase, preventing … Read more
Menadione is a synthetic vitamin K used as a coagulant to treat and prevent bleeding caused by vitamin K deficiency. Structure of Menadione Menadione, also known as vitamin K3, is a synthetic compound with a naphthoquinone structure. Chemical Formula: C₁₀H₆O₂ Mode of Action Provitamin K Activity: Serves as a precursor to active vitamin K forms. … Read more
Definition of Anticoagulants: Anticoagulants are medications that inhibit blood clot formation, thereby reducing the risk of thromboembolic events such as deep vein thrombosis, pulmonary embolism, and stroke. They are essential in preventing abnormal clotting in various medical conditions. Mechanism of Action: Vitamin K Antagonists: Drugs like Warfarin and Anisindione inhibit the enzyme vitamin K epoxide … Read more
Definition of Coagulants: These are agents that promote blood clotting (coagulation) to prevent excessive bleeding. They are used in situations where there is a deficiency in the blood’s natural ability to form clots. Mechanism of Action: Vitamin K-Dependent Pathway: Many coagulants, such as Menadione and Acetomenadione, act as synthetic forms of vitamin K. Vitamin K … Read more
Organized drugs refer to those derived from higher-order structures of plants or organisms. They maintain the complex architecture of the source material, such as leaves roots, stems, bark, seeds, fruits, and flowers. These drugs are typically obtained by physical processes like drying, grinding, or decoction without altering their fundamental structure. Characteristics: Derived from specific plant … Read more
Sources of Drugs: Derived from plants, animals, minerals, microorganisms, and synthetic processes. Sources of Drugs: Provide active compounds for disease prevention and treatment. The development and production of medicinal compounds have historically relied on various natural sources. These sources include plants, animals, marine organisms, microorganisms, and tissue culture techniques. Each source offers unique advantages and … Read more
Introduction to Pharmacognosy: Study of drugs from natural sources, their origin, properties, and uses in medicine. Importance: Introduction to Pharmacognosy links nature with modern drug discovery for safe, effective treatments. Definition Pharmacognosy: The branch of pharmaceutical sciences that deals with the study of drugs of natural origin, encompassing their biological, chemical, biochemical, and physical properties. … Read more
Bioassay of 5-HT (Serotonin): Commonly done using rat fundus strip or uterus for serotonin activity. Bioassay of 5-HT (Serotonin): Measures potency and action via smooth muscle contraction response. Principle 5-HT (Serotonin) also causes smooth muscle contraction in certain tissues (e.g., rat fundus strip, guinea pig ileum). The bioassay measures the contractile response to 5-HT in … Read more
Bioassay of Histamine: Commonly performed using isolated guinea pig ileum to measure contraction response. Bioassay of Histamine: Helps determine potency and concentration of histamine in pharmaceutical preparations. Principle Histamine causes contraction of smooth muscle, notably the guinea pig ileum, and also has vasodilatory and other effects. The classic bioassay measures the contraction of the isolated … Read more
