Peptic Ulcer

Peptic Ulcer

peptic ulcer is a sore that develops on the lining of the stomach, small intestine, or esophagus. It occurs when the protective mucous layer is eroded by stomach acids. Peptic ulcers are classified into gastric ulcers (in the stomach) and duodenal ulcers (in the upper part of the small intestine). Causes of Peptic Ulcer Helicobacter … Read more

Diabetes

Diabetes

Diabetes Introduction Diabetes is a chronic metabolic disorder characterized by high levels of glucose (sugar) in the blood. It occurs due to defects in insulin production, insulin action, or both. Insulin is a hormone produced by the pancreas that helps glucose enter cells to be used for energy. It is classified into several types, with … Read more

Physical Parameters for Bacterial Growth

Physical Parameters for Bacterial Growth

Optimal bacterial growth depends on key physical parameters such as temperature, pH, oxygen levels, and moisture, each varying by species. Temperature required for bacterial growth: Bacteria have different optimal temperature ranges for growth: Psychrophiles: Grow at low temperatures (0-20°C). Mesophiles: Grow at moderate temperatures (20-45°C), including most human pathogens. Thermophiles: Grow at high temperatures (45-80°C). … Read more

Raw Materials Used for Culture Media

Raw Materials Used for Culture Media

Raw Materials Used for Culture Media are essential for growing, isolating, and identifying microorganisms in the laboratory. The composition of these media can vary depending on the specific requirements of the microorganisms being cultured. Here are some of the common raw materials used in the preparation of culture media: Basic Components of Raw Materials Used … Read more

Bacterial Growth Curve

Bacterial Growth Curve

The bacterial growth curve represents the growth of a bacterial population over time in a closed system (batch culture). It has four distinct phases: Lag Phase: Bacteria adapt to new environment. Metabolic activity is high, but cell division is minimal. Synthesis of enzymes, proteins, and other molecules needed for growth. Log (Exponential) Phase: Rapid cell … Read more

Hemophilia

Hemophilia

Hemophilia Introduction Hemophilia is an inherited bleeding disorder characterized by a deficiency in specific clotting factors, leading to prolonged bleeding. The two most common types are Haemophilia A and Haemophilia B. Types Hemophilia A Deficiency: Clotting factor VIII. Genetics: X-linked recessive inheritance, primarily affecting males. Hemophilia B Deficiency: Clotting factor IX. Genetics: X-linked recessive inheritance, … Read more

Hereditary Anemia

Sickle Cell Anemia

Hereditary anemia is caused by genetic mutations that affect the production, structure, or function of RBCs. Common Types of Hereditary Anemia: Sickle Cell Anemia Mutation in the HBB gene leads to abnormal hemoglobin S (HbS). Thalassemia Mutations in genes producing alpha or beta globin chains. Hereditary Spherocytosis Mutations in genes encoding RBC membrane proteins, causing … Read more

Thalassemia

Thalassemia

Thalassemia Introduction Thalassemia is a group of inherited blood disorders caused by mutations affecting hemoglobin production. Results in reduced production of either alpha or beta globin chains, leading to imbalanced globin synthesis, ineffective erythropoiesis, and hemolysis. Categorized into alpha and beta thalassemia based on the affected globin chain. Types of Thalassemia Alpha  Caused by deletions or … Read more

Acquired Anemia

Sickle Cell Anemia

Acquired anemias result from external factors or conditions that affect RBC production or lifespan. Common Types Acquired Anemia Iron Deficiency Anemia Due to inadequate iron intake, absorption issues, or chronic blood loss. Vitamin B12 and Folate Deficiency Anemia Caused by poor dietary intake, malabsorption, or increased demand. Anemia of Chronic Disease Associated with chronic infections, … Read more

Iron Deficiency Anemia

Iron Deficiency Anemia

Iron Deficiency Anemia Introduction Iron Deficiency Anemia occurs  the body lacks enough iron to produce hemoglobin, the protein in red blood cells (RBCs) that carries oxygen from the lungs to the rest of the body. Iron is a critical component of hemoglobin, and its deficiency leads to reduced RBC production and anemia. Causes of Iron … Read more