Chlordiazepoxide

  • Chlordiazepoxide treats anxiety, alcohol withdrawal, and muscle spasms effectively.
  • Chlordiazepoxide is a benzodiazepine enhancing GABA action for calming effects.

Chemical Formula:

  • C₁₆H₁₄ClN₃O

Chemical Structure of Chlordiazepoxide

Mechanism of Chlordiazepoxide:

  • Binds to GABA-A receptor (α, γ subunits) to enhance GABA effect (↑ Cl⁻ influx)
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Uses of Chlordiazepoxide:

  • Generalized anxiety disorder
  • Alcohol withdrawal
  • Preoperative sedation

Side Effects:

  • Drowsiness
  • Impaired coordination
  • Tolerance, dependence
  • Weak muscle relaxant effect

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