- Chlorprothixene is a typical antipsychotic blocking dopamine receptor to reduce psychotic symptoms.
- Its schizophrenia, anxiety, and agitation with calming effects.
Chemical Formula:
- C₁₈H₁₈ClNS
Mechanism of Chlorprothixene:
- D2 receptor antagonist (typical antipsychotic)
- Also blocks H1, M1, α1 receptors
Uses of Chlorprothixene:
- Schizophrenia
- Severe agitation
- Mania (adjunct)
Side Effects:
- Sedation
- Anticholinergic effects
- Moderate EPS
Notes:
- Similar to chlorpromazine in potency
- High sedative effect due to histaminergic blockade
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