Cholinergic Neurotransmitters

  • Cholinergic neurotransmitters refer specifically to acetylcholine (ACh), a key chemical messenger used by certain neurons to communicate with each other or with muscle cells.
  • These neurons are called cholinergic neurons because they release acetylcholine as their primary neurotransmitter.

Cholinergic Neurotransmitters

Function and Importance of Cholinergic Neurotransmitters

  • Acetylcholine is involved in various physiological functions depending on where in the body it’s acting:
    • In the Central Nervous System (CNS): It’s important for learning, memory, attention, and arousal.
    • In the Peripheral Nervous System (PNS):
      • In the somatic nervous system, it stimulates skeletal muscle contraction.
      • In the autonomic nervous system, it:
        • Acts on all preganglionic neurons (both sympathetic and parasympathetic).
        • Acts on postganglionic parasympathetic neurons.
        • In a few cases, it acts on postganglionic sympathetic neurons (like sweat glands).

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