Classification of Anti-Neoplastic Agents

Classification of anti-neoplastic agents based on mechanism and origin, targeting cancer cells and aiding effective cancer therapy.

Classification of Anti-Neoplastic Agents

  • Anti-neoplastic agents are classified based on their mechanism of action and origin.
  • The primary categories include:
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  1. Alkylating Agents

Mechanism:

    • Add alkyl groups to DNA, causing cross-linking and preventing DNA replication and transcription.
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Examples:

  1. Antimetabolites

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Mechanism:

    • Resemble natural substances in cells, disrupting DNA and RNA synthesis by incorporating into the metabolic pathways.

Examples:

  1. Antineoplastic Antibiotics

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Mechanism:

    • Interfere with DNA and RNA within cancer cells, inhibiting their growth and division.
    • Note that these are not traditional antibiotics used for bacterial infections.

Examples:

  1. Plant Alkaloids (Plant-Derived Products)

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Mechanism:

    • Derived from plants, these agents disrupt mitosis (cell division) or inhibit enzymes necessary for cell reproduction.

Examples:

    • Etoposide
    • Vinblastine Sulfate
    • Vincristine Sulfate
  1. Miscellaneous Agents

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Mechanism:

    • Includes drugs that do not fit into the above categories but are effective in cancer treatment.

Examples:

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