Clidinium Bromide

• Clidinium Bromide eases abdominal cramps and IBS symptoms by reducing gastric acid and spasms.
• Clidinium Bromide is an anticholinergic that blocks muscarinic receptors for GI relief.

Chemical Formula:

• C₂₂H₂₆BrNO₃

Mechanism of Action of Clidinium Bromide:

• Antimuscarinic (M1 and M3) → reduces GI motility and secretions
• Does not cross BBB effectively

Therapeutic Uses of Clidinium Bromide:

• Irritable Bowel Syndrome
• Peptic ulcers
• Abdominal cramps (often combined with benzodiazepines like chlordiazepoxide)

Side Effects:

• Constipation
• Dry mouth
• Blurred vision
• Urinary retention

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